No significant effect on bone mineral density by high doses of vitamin D3 given to overweight subjects for one year
Rolf Jorde; Monica Sneve; Peter A. Torjesen; Yngve Figenschau; John‐Bjarne Hansen; Guri Grimnes · 2010 · Nutrition Journal
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: In meta-analyses supplementation with vitamin D appears to reduce incidence of fractures, and in cross-sectional studies there is a positive association between serum 25-hydroxyvitamin D (25(OH)D) levels and bone mineral density (BMD). However, the effect of supplementation with high doses of vitamin D on BMD is more uncertain and could in theory have both positive and negative effects. METHODS: The study was a one year, double blind placebo-controlled intervention trial performed at the University Hospital of North Norway. 421 subjects, 21 - 70 years old, were included and 312 com
Abstract by Rolf Jorde; Monica Sneve; Peter A. Torjesen; Yngve Figenschau; John‐Bjarne Hansen; Guri Grimnes, Nutrition Journal (2010) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/1475-2891-9-1