Effect of irisin on miRNA-associated changes in the PGC-1α/FNDC5/BDNF Axis in an in vitro model of MPP⁺-induced Parkinson's disease.
Karabaş T; Sancar H; Şumnulu D; Ayaz L · 2026 · Molecular biology reports
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Abstract (excerpt)
BACKGROUND: In this study, the neuroprotective potential of irisin was evaluated in an MPP⁺-induced SH-SY5Y in vitro Parkinson’s disease model through miRNA-associated changes related to the PGC-1α/FNDC5/BDNF axis. MATERIAL AND METHOD: An…
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Metadata source: Europe PMC · DOI 10.1007/s11033-026-11861-4