MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours
Małgorzata Bulkowska; Agata Rybicka; Kerem Mert Senses; Katarzyna Ulewicz; Katarzyna Witt; Joanna Szymanska; Bartłomiej Taciak; Robert Klopfleisch · 2017 · BMC Cancer
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Abstract
BACKGROUND: MicroRNAs may act as oncogenes or tumour suppressor genes, which make these small molecules potential diagnostic/prognostic factors and targets for anticancer therapies. Several common oncogenic microRNAs have been found for canine mammary cancer and human breast cancer. On account of this, large-scale profiling of microRNA expression in canine mammary cancer seems to be important for both dogs and humans. METHODS: Expression profiles of 317 microRNAs in 146 canine mammary tumours of different histological type, malignancy grade and clinical history (presence/absence of metastases)
Abstract by Małgorzata Bulkowska; Agata Rybicka; Kerem Mert Senses; Katarzyna Ulewicz; Katarzyna Witt; Joanna Szymanska; Bartłomiej Taciak; Robert Klopfleisch, BMC Cancer (2017) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12885-017-3751-1