Consistent Efficacy of Vutrisiran Across Sexes in Transthyretin Cardiac Amyloidosis: Evidence from the HELIOS-B Trial.
Mansell J; Wang X; Jering KS; Claggett B; Zaroui A; Ishizu T; Eiros R; Jay PY · 2026 · European journal of heart failure
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Sex differences in transthyretin cardiac amyloidosis (ATTR-CM) are increasingly recognised; however, women are underrepresented in trials and sex-specific treatment effects remain incompletely understood. We evaluated sex differences in…
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Metadata source: Europe PMC · DOI 10.1093/ejhf/xuag208