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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 176

Regionally Specific and Genome-Wide Analyses Conclusively Demonstrate the Absence of CpG Methylation in Human Mitochondrial DNA

Elizabeth E. Hong; Cindy Yen Okitsu; Andrew D. Smith; Chih‐Lin Hsieh · 2013 · Molecular and Cellular Biology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Although CpG methylation clearly distributes genome-wide in vertebrate nuclear DNA, the state of methylation in the vertebrate mitochondrial genome has been unclear. Several recent reports using immunoprecipitation, mass spectrometry, and…

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Metadata source: OpenAlex · DOI 10.1128/mcb.00220-13