Systemic pharmacokinetics of acitretin, etretinate, isotretinoin, and acetylenic retinoids in guinea pigs and obese rats.
Du-Shieng Chien; R. Sandri; D. Tang-Liu · 1992 · Drug Metabolism And Disposition
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Etretinate, a highly lipophilic retinoid, is known to accumulate in the human body with a slow systemic elimination (half-life approximately 100 days) after long-term treatment. Retinoids with high lipophilicity and slow body elimination…
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Metadata source: Semantic Scholar · DOI 10.1016/s0090-9556(25)08568-x