PNPLA3-I148M reduces hepatic triacylglycerol secretion and mitigates diet induced left ventricular diastolic dysfunction.
Butcko AJ; Adeshina KA; Kamali P; Teskey G; Rahman AA; Jaster JV; Tiwari N; Singh NK · 2026 · Scientific reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
PNPLA3-I148M, the greatest genetic determinant for metabolic dysfunction-associated steatotic liver disease (MASLD), paradoxically associates with reduced cardiovascular disease (CVD); however, the mechanisms are poorly understood. To…
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Metadata source: Europe PMC · DOI 10.1038/s41598-026-47839-2