Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
Yan Wang; Fabiana Quagliarini; Viktoria Gusarova; Jesper Gromada; David M. Valenzuela; Jonathan C. Cohen; Helen H. Hobbs · 2013 · Proceedings of the National Academy of Sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Angiopoietin-like protein (ANGPTL)8 (alternatively called TD26, RIFL, Lipasin, and Betatrophin) is a newly recognized ANGPTL family member that has been implicated in both triglyceride (TG) and glucose metabolism. Hepatic overexpression of…
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Metadata source: OpenAlex · DOI 10.1073/pnas.1315292110