e-ISSN: Pending
Replication FailureOpen accessMedicine· cited by 1,074

Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial

Mark R. Gilbert; Meihua Wang; Kenneth Aldape; Roger Stupp; Monika E. Hegi; Kurt A. Jaeckle; Terri S. Armstrong; Jeffrey S. Wefel · 2013 · Journal of Clinical Oncology

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

PURPOSE: Radiotherapy with concomitant and adjuvant temozolomide is the standard of care for newly diagnosed glioblastoma (GBM). O(6)-methylguanine-DNA methyltransferase (MGMT) methylation status may be an important determinant of…

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Metadata source: OpenAlex · DOI 10.1200/jco.2013.49.6968