The Single-Prolonged Stress Model Fails to Produce Behavioral or Corticosterone Alterations in Rats.
McGuier M; Bragg E; Holtzheimer P; Doucette W · 2026 · eNeuro
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
There is a critical need for robust and reliable preclinical models for posttraumatic stress disorder (PTSD) to better understand pathophysiological mechanisms and support the development of novel treatments. The single prolonged stress…
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Metadata source: Europe PMC · DOI 10.1523/eneuro.0168-25.2025