Effectiveness of Metformin in Preventing Herpes Zoster Among Japanese Patients With Type 2 Diabetes: A Target Trial Emulation.
Hiroki S; Fukasawa T; Yokogawa K; Kawakami K · 2025 · Journal of medical virology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Patients with type 2 diabetes have a higher risk of herpes zoster (HZ). Although metformin may reduce this risk via immunomodulatory effects, prior evidence is limited by confounding by indication and an unclear causal estimand. We aimed…
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Metadata source: Europe PMC · DOI 10.1002/jmv.70606