Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
Larisa I. Labzin; Keng Yih Chew; Kathrin Eschke; Xiaohui Wang; Tyron Esposito; Claudia J. Stocks; James Rae; Ralph Patrick · 2023 · Science Signaling
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on a subset of macrophages at sites of SARS-CoV-2 infection in…
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Metadata source: OpenAlex · DOI 10.1126/scisignal.abq1366