FADS2 Polymorphisms Modify the Effect of Breastfeeding on Child IQ
Colin Steer; George Davey Smith; Pauline Emmett; Joseph R. Hibbeln; Jean Golding · 2010 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Breastfeeding is important for child cognitive development. A study by Caspi et al has suggested that rs174575 within the FADS2 gene moderates this effect so that children homozygous in the minor allele (GG genotype) have similar IQs irrespective of feeding method. METHODS AND PRINCIPAL FINDINGS: In our study of 5934 children aged 8 years, no genetic main effect with IQ was found for rs174575. However, an interaction with this polymorphism was observed such that breastfed GG children performed better than their formula fed counterparts by an additional 5.8 points [1.4, 10.1] (inter
Abstract by Colin Steer; George Davey Smith; Pauline Emmett; Joseph R. Hibbeln; Jean Golding, PLoS ONE (2010) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0011570