Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.
Roemhild K; Li Y; Barmin RA; Dadfar SM; Savina E; Lindelauf K; Moeckel D; Rama E · 2026 · Journal of controlled release : official journal of the Controlled Release Society
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Macrophages are key regulators of the tumor microenvironment (TME) and attractive targets for nanomedicine therapies. Because intracellular iron can promote pro-inflammatory macrophage polarization, superparamagnetic iron oxide…
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Metadata source: Europe PMC · DOI 10.1016/j.jconrel.2026.114726