Safety and efficacy of autologous haematopoietic stem-cell transplantation with low-dose cyclophosphamide mobilisation and reduced intensity conditioning versus standard of care in refractory Crohn's disease (ASTIClite): an open-label, multicentre, randomised controlled trial.
Lindsay JO; Hind D; Swaby L; Berntsson H; Bradburn M; Bannur C U; Byrne J; Clarke C · 2024 · The lancet. Gastroenterology & hepatology
WASTE classifies this as Failed Experiment Report · AI classification, approximate
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Abstract (excerpt)
Background A previous controlled trial of autologous haematopoietic stem-cell transplantation (HSCT) in patients with refractory Crohn's disease did not meet its primary endpoint and reported high toxicity. We aimed to assess the safety…
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Metadata source: Europe PMC · DOI 10.1016/s2468-1253(23)00460-0