Metformin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: a prospective, placebo-controlled, randomized study
Susanna Wiegand; Dagmar l’Allemand; Hanna Hübel; Heiko Krude; Mareike Bürmann; Peter Martus; Annette Grüters; Reinhard W. Holl · 2010 · European Journal of Endocrinology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVE: To study whether metformin reduces obesity, homeostasis model assessment for insulin resistance index (HOMA-IR), and the metabolic syndrome (MtS) in obese European adolescents in addition to previous unsuccessful lifestyle…
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Metadata source: OpenAlex · DOI 10.1530/eje-10-0570