Blood Biomarkers in Moderate-To-Severe Traumatic Brain Injury: Potential Utility of a Multi-Marker Approach in Characterizing Outcome
Alex P. Di Battista; John E. Buonora; Shawn G. Rhind; Michael G. Hutchison; Andrew Baker; Sandro Rizoli; Ramon Diaz‐Arrastia; Gregory P. Mueller · 2015 · Frontiers in Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Blood biomarkers are valuable tools for elucidating complex cellular and molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of biomarkers could aid in the identification and characterization of initial injury and secondary pathological processes. This study characterized the prognostic performance of a recently developed multi-marker panel of circulating biomarkers that reflect specific pathogenic mechanisms including neuroinflammation, oxidative damage, and neuroregeneration, in moderate-to-severe TBI patients. MATERIALS AND METHODS: Periphera
Abstract by Alex P. Di Battista; John E. Buonora; Shawn G. Rhind; Michael G. Hutchison; Andrew Baker; Sandro Rizoli; Ramon Diaz‐Arrastia; Gregory P. Mueller, Frontiers in Neurology (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fneur.2015.00110