Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report
Patrick J. Leavey; Nadia N. Laack; Mark D. Krailo; Allen Buxton; R. Lor Randall; Steven G. DuBois; Damon R. Reed; Holcombe E. Grier · 2021 · Journal of Clinical Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
PURPOSE The primary aim of this phase III randomized trial was to test whether the addition of vincristine, topotecan, and cyclophosphamide (VTC) to interval compressed chemotherapy improved survival outcomes for patients with previously…
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Metadata source: OpenAlex · DOI 10.1200/jco.21.00358