A Phase 1b/2, Randomised, Placebo-controlled Study to Evaluate Safety, Tolerability, Efficacy, and Immunogenicity of VTP-200, a Chimpanzee Adenovirus and Modified Vaccinia Ankara-vectored Multigenotype High-Risk Human Papillomavirus Vaccine in Women with Low-grade Cervical Lesions.
Hellner K; Simon P; De Sutter P; Vahula KL; Briggs P; Kiisla Ü; Russell M; Newton C · 2025 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background The clearance of high-risk oncogenic HPV (hrHPV) and related cervical lesions is associated with the development of a robust T cell response. Therapeutic vaccination that induces HPV antigen-specific T cells is a promising…
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Metadata source: Europe PMC · DOI 10.1093/cid/ciaf658