Parkin Interacts with Ambra1 to Induce Mitophagy
Cindy Van Humbeeck; Tom Cornelissen; Hilde Hofkens; Wim Mandemakers; Kris Gevaert; Bart De Strooper; Wim Vandenberghe · 2011 · Journal of Neuroscience
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Mutations in the gene encoding Parkin are a major cause of recessive Parkinson's disease. Recent work has shown that Parkin translocates from the cytosol to depolarized mitochondria and induces their autophagic removal (mitophagy).…
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Metadata source: OpenAlex · DOI 10.1523/jneurosci.1917-11.2011