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Negative / Null Result ReportOpen accessMedicine· cited by 10

Addition of chemotherapy to intensity-modulated radiotherapy does not improve survival in stage II nasopharyngeal carcinoma patients

Fangzheng Wang; Jiang Chuner; Quanquan Sun; Ye Zhimin; Tongxin Liu; Liu Jiping; Masoto Sakamoto; Peng Wu · 2018 · Journal of Cancer

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

In this study, we examined whether combining neoadjuvant chemotherapy (NAC) and/or concurrent chemotherapy (CC) with intensity-modulated radiotherapy (IMRT) improved survival in patients with stage II nasopharyngeal carcinoma (NPC). Two hundred forty-two stage II NPC patients were enrolled between May 2008 and April 2014 and received radical IMRT with simultaneous integrated boost technique using 6 MV photons; some patient groups also received chemotherapy every 3 weeks for 2-3 cycles. The median follow-up duration was 69 months for all patients. At the last follow-up, 18 patients had experien

Abstract by Fangzheng Wang; Jiang Chuner; Quanquan Sun; Ye Zhimin; Tongxin Liu; Liu Jiping; Masoto Sakamoto; Peng Wu, Journal of Cancer (2018) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.7150/jca.25042