Microstructural White Matter Characteristics in Parkinson's Disease With Depression: A Diffusion Tensor Imaging Replication Study
Colleen Lacey; Lisa Ohlhauser; Jodie R. Gawryluk · 2019 · Frontiers in Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background Clarifying the neuropathology of depression as a symptom of Parkinson's disease (PD) has been the goal of recent neuroimaging studies; however, results have been conflicting and lack replication. The purpose of the current study was to replicate recent methods that have used diffusion tensor imaging (DTI) to compare individuals with PD with and without depression and to extend previous findings to allow for a better understanding of the results. Methods Thirty-seven participants with de novo PD were retrieved from the Parkinson's Progression Marker's Initiative (PPMI) and were separ
Abstract by Colleen Lacey; Lisa Ohlhauser; Jodie R. Gawryluk, Frontiers in Neurology (2019) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fneur.2019.00884