The effect of switching antipsychotics to aripiprazole versus paliperidone on weight/cardiometabolic parameters: 18-month follow-up findings from the European Long-acting Antipsychotics in Schizophrenia Trial (EULAST).
de Boer N; Vučko Z; Koster DI; van der Horst M; Davidson M; Cahn W; Luykx JJ · 2026 · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Antipsychotic-induced weight gain (AiWG) is a common, burdensome adverse effect. Switching to antipsychotics with lower metabolic risks, such as aripiprazole, is recommended, but long-term data is limited. Long-acting injectables (LAIs)…
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Metadata source: Europe PMC · DOI 10.1016/j.euroneuro.2025.11.014