Fluid balance control in critically ill patients: results from POINCARE-2 stepped wedge cluster-randomized trial
Pierre‐Édouard Bollaert; Alexandra Monnier; Francis Schneider; Laurent Argaud; Julio Badié; Claire Charpentier; Ferhat Meziani; M. Bemer · 2023 · Critical Care
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: In critically ill patients, positive fluid balance is associated with excessive mortality. The POINCARE-2 trial aimed to assess the effectiveness of a fluid balance control strategy on mortality in critically ill patients. METHODS: POINCARE-2 was a stepped wedge cluster open-label randomized controlled trial. We recruited critically ill patients in twelve volunteering intensive care units from nine French hospitals. Eligible patients were ≥ 18 years old, under mechanical ventilation, admitted to one of the 12 recruiting units for > 48 and ≤ 72 h, and had an expected length of stay
Abstract by Pierre‐Édouard Bollaert; Alexandra Monnier; Francis Schneider; Laurent Argaud; Julio Badié; Claire Charpentier; Ferhat Meziani; M. Bemer, Critical Care (2023) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s13054-023-04357-1