Prime Editing Exhibits Limited Genome-Wide Off-Target Effects in Cellular and Embryonic Gene Editing.
Zheng J; Wu M; Wang X; Zuo Z; Zhou C; Zuo E; Lu Y · 2026 · Cells
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
Prime editing (PE) is a precise genome-editing technology that avoids double-strand breaks, holding great promise for clinical and agricultural applications. However, its genome-wide off-target effects are not fully understood, raising…
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Metadata source: Europe PMC · DOI 10.3390/cells15050438