Effects of Sacubitril/Valsartan vs Irbesartan on Urine Tubular Biomarkers in CKD: Findings from the UK HARP-III Trial.
Goonasekera MA; Malijan GB; Sardell RJ; Staplin N; Storey BS; Chapman D; Hill M; Moffat S · 2026 · American journal of nephrology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Introduction Sacubitril/valsartan shows benefits in heart failure and may have kidney protective effects. Its impact on kidney tubular health in chronic kidney disease (CKD) remains unclear. We evaluated the effects of sacubitril/valsartan…
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Metadata source: Europe PMC · DOI 10.1159/000552348