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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 10

The gut–brain connection: microbes’ influence on mental health and psychological disorders

Pegah Ataei; Hamidreza Kalantari; Tamara S. Bodnar; Raymond J. Turner · 2026 · Frontiers in Microbiomes

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

The human gut microbiome has emerged as a pivotal modulator of brain function and mental health, acting through intricate bidirectional communication along the gut-brain axis. Mounting evidence suggests that microbial communities influence neurodevelopment, neurotransmission, and behavior via pathways involving the vagus nerve, immune signaling, and microbiota-derived metabolites such as short-chain fatty acids and neurotransmitter precursors. This review critically examines the mechanistic underpinnings of microbiota-brain communication and evaluates current findings linking dysbiosis to psyc

Abstract by Pegah Ataei; Hamidreza Kalantari; Tamara S. Bodnar; Raymond J. Turner, Frontiers in Microbiomes (2026) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3389/frmbi.2025.1701608