Dysregulated brain-gut axis in the setting of traumatic brain injury: review of mechanisms and anti-inflammatory pharmacotherapies
Mahmoud G. El Baassiri; Zachariah Raouf; Sarah Badin; Alejandro Escobosa; Chhinder P. Sodhi; Isam W. Nasr · 2024 · Journal of Neuroinflammation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Traumatic brain injury (TBI) is a chronic and debilitating disease, associated with a high risk of psychiatric and neurodegenerative diseases. Despite significant advancements in improving outcomes, the lack of effective treatments underscore the urgent need for innovative therapeutic strategies. The brain-gut axis has emerged as a crucial bidirectional pathway connecting the brain and the gastrointestinal (GI) system through an intricate network of neuronal, hormonal, and immunological pathways. Four main pathways are primarily implicated in this crosstalk, including the systemic immune syste
Abstract by Mahmoud G. El Baassiri; Zachariah Raouf; Sarah Badin; Alejandro Escobosa; Chhinder P. Sodhi; Isam W. Nasr, Journal of Neuroinflammation (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12974-024-03118-3