Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome
Michelle L. O’Donoghue; Eugene Braunwald; Harvey D. White; Dylan P. Steen; Mary Ann Lukas; Elizabeth Tarka; Philippe Gabríel Steg; Judith S. Hochman · 2014 · JAMA
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
IMPORTANCE: Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme. OBJECTIVE: To…
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Metadata source: OpenAlex · DOI 10.1001/jama.2014.11061