Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease
J. Hoozemans; E. S. van Haastert; Robert Veerhuis; T. Arendt; W. Scheper; P. Eikelenboom; A. Rozemuller · 2005 · Journal of Neuroinflammation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Neuronal expression of cyclooxygenase-2 (COX-2) and cell cycle proteins is suggested to contribute to neurodegeneration during Alzheimer's disease (AD). The stimulus that induces COX-2 and cell cycle protein expression in AD is still…
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Metadata source: Semantic Scholar · DOI 10.1186/1742-2094-2-27