High-Dose Versus Standard-Dose Intensity-Modulated Radiotherapy With Concurrent Paclitaxel Plus Carboplatin for Patients With Thoracic Esophageal Squamous Cell Carcinoma: A Randomized, Multicenter, Open-Label, Phase 3 Superiority Trial
Jing You; Shuchai Zhu; Jiancheng Li; Jie Li; Junyue Shen; Yidian Zhao; Xiaomin Li; Lin Jia · 2022 · International Journal of Radiation Oncology*Biology*Physics
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
PurposeThe standard dose (SD) of definitive concurrent chemoradiotherapy (dCRT) remains 50.4 Gy in patients with esophageal cancer; a higher dose, when applied with conventional radiation therapy techniques, increases toxicities without…
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Metadata source: OpenAlex · DOI 10.1016/j.ijrobp.2022.11.006