Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies
Ruben A. Mesa; Jean‐Jacques Kiladjian; Srđan Verstovšek; Haifa Kathrin Al‐Ali; Jason Gotlib; Heinz Gisslinger; R. S. Levy; A. Siulnik · 2013 · Haematologica
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“Prior to Janus kinase inhibitors, available therapies for myelofibrosis were generally supportive and did not improve survival.”
Abstract (excerpt)
Prior to Janus kinase inhibitors, available therapies for myelofibrosis were generally supportive and did not improve survival. This analysis compares efficacy outcomes of patients with myelofibrosis in the control arms (placebo [n=154]…
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Metadata source: OpenAlex · DOI 10.3324/haematol.2013.087650