Negative / Null Result ReportOpen accessMedicine· cited by 265

Comparison of T1 mapping techniques for ECV quantification. Histological validation and reproducibility of ShMOLLI versus multibreath-hold T1 quantification equilibrium contrast CMR

Marianna Fontana; Steve K White; Sanjay M Banypersad; Daniel Sado; Viviana Maestrini; Andrew Flett; Stefan K. Piechnik; Stefan Neubauer · 2012 · Journal of Cardiovascular Magnetic Resonance

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: Myocardial extracellular volume (ECV) is elevated in fibrosis or infiltration and can be quantified by measuring the haematocrit with pre and post contrast T1 at sufficient contrast equilibrium. Equilibrium CMR (EQ-CMR), using a bolus-infusion protocol, has been shown to provide robust measurements of ECV using a multibreath-hold T1 pulse sequence. Newer, faster sequences for T1 mapping promise whole heart coverage and improved clinical utility, but have not been validated. METHODS: Multibreathhold T1 quantification with heart rate correction and single breath-hold T1 mapping using

Abstract by Marianna Fontana; Steve K White; Sanjay M Banypersad; Daniel Sado; Viviana Maestrini; Andrew Flett; Stefan K. Piechnik; Stefan Neubauer, Journal of Cardiovascular Magnetic Resonance (2012) — licensed CC BY 4.0.

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