e-ISSN: Pending
Negative / Null Result ReportMedicine

Aminoglycosides induce immune activation but is insufficient for systemic viral control: a double-blind randomized-controlled clinical trial.

Sivanandam P; Syenina A; Chan YF; Ng DH; Gan ES; Yee JX; Tham CY; Tan HC · 2026 · Communications medicine

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background Mucosally-applied aminoglycosides have demonstrated host-directed antiviral activity in preclinical models through induction of interferon-stimulated genes (ISGs). However, it remains unknown if systemically administered…

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Metadata source: Europe PMC · DOI 10.1038/s43856-026-01678-4