Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model
Kyle J. Bednar; Elena Shanina; Romain Ballet; Edward P Connors; Shiteng Duan; Joana Juan; Britni M. Arlian; Michael D. Kulis · 2017 · The Journal of Immunology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract CD22, a sialic acid–binding Ig-type lectin (Siglec) family member, is an inhibitory coreceptor of the BCR with established roles in health and disease. The restricted expression pattern of CD22 on B cells and most B cell lymphomas…
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Metadata source: OpenAlex · DOI 10.4049/jimmunol.1700898