The mitochondrial-targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial-apoptotic but not necroptotic signalling during ovarian cancer.
Khajehzadehshoushtar S; Delfinis LJ; Rahman FA; Garibotti MC; Gandhi S; Brahmbhatt AN; Morris BA; Garlisi B · 2025 · The Journal of physiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The degree to which mitochondrial-linked programmed cell death pathways contribute to skeletal muscle atrophy during cancer remains unknown. Here we combined a novel and robust mouse model of metastatic ovarian cancer with chronic…
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Metadata source: Europe PMC · DOI 10.1113/jp287912