Implantation of a Continuous-Flow Left Ventricular Assist Device During Cardiopulmonary Bypass Is Associated with a Significant and Transient Acute Thromboinflammatory Response.
Gerogianni A; Sørensen G; Hoel TN; McAdam KE; Schjalm C; Gude E; Sjöström DJ; Henriksson C · 2026 · International journal of molecular sciences
WASTE classifies this as Abandoned Hypothesis · AI classification, approximate
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Abstract (excerpt)
Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure but may compromise immune integrity. Mechanical shear stress and surface-induced innate immune activation can trigger bleeding and…
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Metadata source: Europe PMC · DOI 10.3390/ijms27104594