Short-term transcutaneous vagus nerve stimulation increases pupil size but does not affect EEG alpha power: A replication of Sharon et al. (2021, Journal of Neuroscience)
Beth Lloyd; Franz Wurm; Roy de Kleijn; Sander Nieuwenhuis · 2023 · Brain stimulation
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract
BackgroundTranscutaneous auricular vagus nerve stimulation (taVNS) has been tested as a potential treatment for pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced activation of the locus coeruleus and other neuromodulator systems. However, unlike for invasive VNS in rodents, there is little evidence for an effect of taVNS on noradrenergic activity.ObjectiveWe attempted to replicate recently published findings by Sharon et al. (2021), showing that short bursts of taVNS transiently increased pupil size and decreased EEG alpha power, two correl
Abstract by Beth Lloyd; Franz Wurm; Roy de Kleijn; Sander Nieuwenhuis, Brain stimulation (2023) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.brs.2023.06.010