Negative / Null Result ReportOpen accessMedicine· cited by 51

Is Doppler ultrasound of additional value to gray-scale ultrasound in differentiating malignant and benign thyroid nodules?

Pedro Weslley Rosário; Alexandre Lemos Silva; Michelle Aparecida Ribeiro Borges; Maria Regina Calsolari · 2015 · Archives of Endocrinology and Metabolism

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

The objective of this study was to evaluate whether Doppler ultrasound (DUS) is of additional value to gray-scale ultrasound (GSUS) in predicting the benign or malignant nature of thyroid nodules. A total of 1,502 solid thyroid nodules ≥ 10 mm were evaluated. Suspicious vascularity (predominantly or exclusively central blood flow) was observed in only 5% of the nodules. This finding showed 96% specificity, but only 15% sensitivity. GSUS alone showed sensitivity and specificity of 88.7% and 68.2%, respectively, which did not improve with the addition of DUS (sensitivity of 89.4% and specificity

Abstract by Pedro Weslley Rosário; Alexandre Lemos Silva; Michelle Aparecida Ribeiro Borges; Maria Regina Calsolari, Archives of Endocrinology and Metabolism (2015) — licensed CC BY 4.0.

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