Semaglutide for the treatment of cognitive dysfunction in major depressive disorder: A randomized clinical trial.
Badulescu S; Gill H; Shah H; Brudner R; Phan L; Di Vincenzo JD; Tabassum A; Armanyous M · 2026 · Med (New York, N.Y.)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Evidence suggests that glucagon-like peptide 1 receptor agonists (GLP-1RAs) might have pro-cognitive effects. No prior study has evaluated the efficacy and safety of a GLP-1RA for the treatment of cognitive dysfunction in adults…
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Metadata source: Europe PMC · DOI 10.1016/j.medj.2025.100916