Negative / Null Result Report2021
Effect of Metal–Organic Framework (MOF) Database Selection on the Assessment of Gas Storage and Separation Potentials of MOFs
Angewandte Chemie International Edition
Failure-mode index
Negative results in Chemistry
28 indexed negative results, null findings, and replication failures in Chemistry. Each entry is a real published study whose primary finding was negative — learn what already failed before you repeat it.
Most-cited failures in Chemistry
Negative / Null Result Report2012
Olive Leaf Extract as a Hypoglycemic Agent in Both Human Diabetic Subjects and in Rats
Journal of Medicinal Food
Negative / Null Result Report2018
MoMo: discovery of statistically significant post-translational modification motifs
Bioinformatics
Negative / Null Result Report2019
Reliable Identification of Significant Differences in Differential Hydrogen Exchange-Mass Spectrometry Measurements Using a Hybrid Significance Testing Approach
Analytical Chemistry
Negative / Null Result Report2010
Significant Association between Sulfate-Reducing Bacteria and Uranium-Reducing Microbial Communities as Revealed by a Combined Massively Parallel Sequencing-Indicator Species Approach
Applied and Environmental Microbiology
Negative / Null Result Report2014
Quantitative, Time-Resolved Proteomic Analysis by Combining Bioorthogonal Noncanonical Amino Acid Tagging and Pulsed Stable Isotope Labeling by Amino Acids in Cell Culture
Molecular & Cellular Proteomics
Negative / Null Result Report2020
Unsymmetrical Strategy Makes Significant Differences in α‐Diimine Nickel and Palladium Catalyzed Ethylene (Co)Polymerizations
ChemCatChem
Negative / Null Result Report2017
Comparative evaluation of label‐free quantification methods for shotgun proteomics
Rapid Communications in Mass Spectrometry
Negative / Null Result Report2015
Significant Differences Characterise the Correlation Coefficients between Biocide and Antibiotic Susceptibility Profiles in Staphylococcus aureus
Current Pharmaceutical Design
Negative / Null Result Report2013
Intrinsic Optical Activity and Conformational Flexibility: The Role of Size-Dependent Ring Morphology in Model Cycloketones
The Journal of Physical Chemistry A
Negative / Null Result Report2025
Data‐Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome
PROTEOMICS
Replication Failure2025
Herbify: an ensemble deep learning framework integrating convolutional neural networks and vision transformers for precise herb identification
Plant Methods
Replication Failure2026
Photochemical synthesis of oxiranes using DABSO-activated sulfinates and allylic peroxides
Nature Communications
Negative / Null Result Report2016
Net Analyte Signal-based Quantitative Determination of Fusel Oil in Korean Alcoholic Beverage Using FT-NIR Spectroscopy
Journal of Biosystems Engineering
Replication Failure2025
Synthesis of enantioenriched atropisomers by biocatalytic deracemization
Nature
Negative / Null Result Report2025
Catalytic Oxidative Ligand Transfer of Rh-Carbynoids and Alkyl Iodides
Journal of the American Chemical Society
Negative / Null Result Report2026
Rapid Determination of Soybean Protein Content by Near-Infrared Spectroscopy Coupled with Multi-Learner Ensemble Wavelength Selection
Foods
Negative / Null Result Report2021
Contribution of the Locus of Heat Resistance to Growth and Survival of Escherichia coli at Alkaline pH and at Alkaline pH in the Presence of Chlorine
Microorganisms
Negative / Null Result Report2014
Efeito dos ácidos hialurônicos como condroprotetores em modelo experimental de osteoartrose
Negative / Null Result Report1981
Influence de l’Agitation Mécanique sur les Reactions Chimiques Oscillantes en Présence d’Oxygène ou d’Azote
CHIMIA
Negative / Null Result Report2012
Calculations of optical rotation: Influence of molecular structure
Journal of the Serbian Chemical Society
Abandoned Hypothesis2018
Evaluation of selected quality parameters of reduced salt frankfurters
Negative / Null Result Report2025
A Practical Approach for Measuring Chemical Oxygen Demand (COD) of Fats, Oils, and Grease (FOG) Using Tween 80 in Wastewater
ChemEngineering
Negative / Null Result Report2022
Biomaterials Based on Carbon Nanotube Nanocomposites of Poly(styrene- b -isobutylene- b -styrene): The Effect of Nanotube Content on the Mechanical Properties, Biocompatibility and Hemocompatibility
Nanomaterials
Negative / Null Result Report2020
PCSK9 concentrations in different stages of subclinical atherosclerosis and their relationship with inflammation
Open Chemistry
Methods Dead-End2017
PEMANFAATAN BUNGKIL BIJI KARET SEBAGAI EKSTENDER PEREKAT PADA KAYU LAPIS PULAI (Alstonia angustiloba Miq.)
Negative / Null Result Report2011
Trehalose may prevent postsurgical adhesions in a rabbit model of hysterotomy.
Journal of Veterinary Medical Science
Negative / Null Result Report2020