Failed Experiment ReportOpen accessMedicine
Se-Hee Min, Suk Hyung Choe, Won Shik Kim et al. · 2022 · Scientific Reports
Abstract Flap failure after microvascular reconstructive surgery is a rare but devastating complication caused by reperfusion injury and tissue hypoperfusion. Remote ischemic conditioning (RIC) provides protection against ischemia/reperfusion injury and reduces tissue infarction. We hypothesized that RIC would enhance flap oxygenation and exert organ-protective effects during head and neck free flap reconstructive surgery. Adult patients undergoing free flap transfer surgery for head and neck cancer were randomized to receive either RIC or sham-RIC during surgery. RIC consisted of four cycles
View details →DOI: 10.1038/s41598-022-12374-3 Failed Experiment ReportOpen accessMedicine
Vaisitti F, Sobrero S, Rudella S et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
Objectives The fissure last (FL) technique described in 1998 has the goal of minimizing postoperative airleak leaving the stapling of the fissure as the last step. The aim of this study was the reduction in airleak may be already evident…
View details →DOI: 10.1093/icvts/ivag039 Failed Experiment Report
Laure T, Boffo M, Konigorski S et al. · 2026 · Preprint
BackgroundOne in four university students face mental health challenges, underscoring the need for effective support systems. Within Erasmus University Rotterdam student wellbeing initiative, we developed a mobile intervention providing…
View details →DOI: 10.31234/osf.io/pbcv4_v2 Failed Experiment ReportMedicine
Chichareon P, Suwannanon R, Thungthienthong M et al. · 2026 · British journal of clinical pharmacology
Background Left ventricular hypertrophy (LVH) contributes to a substantial risk of adverse outcomes in patients with coronary artery disease (CAD). Inflammation is one of the mechanisms responsible for LVH progression. The study aimed to…
View details →DOI: 10.1002/bcp.70470 Failed Experiment ReportOpen accessMedicine
Sawada A, Yoneta K, Togashi E et al. · 2024 · Journal of physical therapy science
[Purpose] In gastric cancer patients, low muscle mass decreases overall survival and quality of life (QOL). Resistance exercise with leucine-enriched essential amino acid (LEAA) supplementation may prevent muscle mass loss. This study was…
View details →DOI: 10.1589/jpts.36.218 Failed Experiment ReportOpen accessMedicine
Srivastava S, Kharkar VR, More S et al. · 2024 · Journal of clinical and experimental dentistry
Background Absorbable gelatin sponges are able to reduce the incidence of post-extraction complications when soaked with antimicrobial agents. However, the drawbacks associated with the injudicious use of antibiotics warrant the need to…
View details →DOI: 10.4317/jced.61640 Failed Experiment ReportMedicine
Mwenechanya M, Tembo AM, Chomba E et al. · 2026 · BJOG : an international journal of obstetrics and gynaecology
Objective To evaluate if the effect of low-dose aspirin (LDA) commenced between 6 and 13 weeks of gestational age (GA) on preterm delivery (PTD) is modified by total exposure. Design Post hoc analysis of a randomized controlled trial.…
View details →DOI: 10.1111/1471-0528.70244 Failed Experiment ReportMedicine
Zampino S, Hosler R, Brown K et al. · 2026 · The Journal of cardiovascular nursing
Background Reiki plus manual therapy are utilized to improve relaxation, sleep, emotional state, and pain. Evidence within hospital settings was limited, and previous studies had weak designs. Objective The purpose of this study was to…
View details →DOI: 10.1097/jcn.0000000000001334 Failed Experiment ReportOpen accessMedicine
Georgiadis AG, Schavee PE, Koester TM et al. · 2025 · JB & JS open access
Background Cast removal may produce pain or anxiety in children. Virtual reality (VR) has been studied in other pediatric settings, but little evidence exists for its use during pediatric cast removal. Methods A randomized controlled trial…
View details →DOI: 10.2106/jbjs.oa.24.00244 Failed Experiment ReportMedicine
Hennigar SR, Miller KM, Murphy RD et al. · 2026 · The Journal of nutrition
Background Iron deficiency (ID) is associated with decreased appetite and altered mood, which can contribute to feelings of early satiety and reduced overall well-being. Few studies have examined differences in appetite, satiety, and mood…
View details →DOI: 10.1016/j.tjnut.2026.101559 Failed Experiment ReportOpen accessMedicine
Wallon S, Williamsson C, Karlsson V et al. · 2026 · Trials
Background Routine use of surgical drains after abdominal operations has largely been abandoned over the past decades. Studies have failed to demonstrate benefits of routine drainage following liver, gallbladder, gastric, and colorectal…
View details →DOI: 10.1186/s13063-026-09762-9 