Negative / Null Result ReportMedicine
Fiszdon JM, Wang K, Fulford D et al. · 2026 · Journal of the International Neuropsychological Society : JINS
Objectives Poor social function in people with psychosis has been linked to impairments in social cognition and neurocognition, which in turn have been identified as promising treatment targets. We developed a novel social cognitive…
View details →DOI: 10.1017/s1355617726102070 Negative / Null Result ReportOpen accessMedicine
Hostrup M, Jessen S, Tischer SG et al. · 2026 · Scandinavian journal of medicine & science in sports
Misuse of beta 2 -agonists to promote leanness is increasingly reported among young men undertaking resistance training. However, preclinical models demonstrate adverse cardiac remodeling with high-dose beta 2 -agonist. We investigated…
View details →DOI: 10.1111/sms.70302 Failed Experiment ReportMedicine
Mwenechanya M, Tembo AM, Chomba E et al. · 2026 · BJOG : an international journal of obstetrics and gynaecology
Objective To evaluate if the effect of low-dose aspirin (LDA) commenced between 6 and 13 weeks of gestational age (GA) on preterm delivery (PTD) is modified by total exposure. Design Post hoc analysis of a randomized controlled trial.…
View details →DOI: 10.1111/1471-0528.70244 Negative / Null Result ReportMedicine
Agarwal R · 2026 · American journal of hypertension
Background The mechanism of hypertension associated with erythropoiesis-stimulating agents in chronic kidney disease (CKD) is complex and remains poorly understood. Methods Here, anemic hypertensive patients with CKD and well-controlled or…
View details →DOI: 10.1093/ajh/hpaf200 Negative / Null Result ReportMedicine
Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine
Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…
View details →DOI: 10.1016/j.accpm.2026.101818 Negative / Null Result ReportMedicine
Kaş Alay G, Mutlu B · 2026 · Games for health journal
Objective To determine the effect of training children with familial Mediterranean fever (FMF) using a mobile game (MG) or training booklet (TB) on self-efficacy, symptom management, and quality of life (HRQoL) compared with a control…
View details →DOI: 10.1177/2161783x251414694 Failed Experiment ReportMedicine
Zampino S, Hosler R, Brown K et al. · 2026 · The Journal of cardiovascular nursing
Background Reiki plus manual therapy are utilized to improve relaxation, sleep, emotional state, and pain. Evidence within hospital settings was limited, and previous studies had weak designs. Objective The purpose of this study was to…
View details →DOI: 10.1097/jcn.0000000000001334 Negative / Null Result ReportMedicine
Kolachena V, Priyadarshi M, Singh P et al. · 2026 · Resuscitation
The optimum site of tactile stimulation (TS) during initial steps of neonatal resuscitation in the delivery room (DR) is not well-established. To compare the impact of three different sites of TS (back rub, trunk rub, and sole rub) on…
View details →DOI: 10.1016/j.resuscitation.2026.111190 Negative / Null Result Report
Lee Y, Vazou S, Kim S et al. · 2026 · Preprint
Abstract Exercise is an established strategy for reducing depressive symptoms, yet the psychophysiological mechanisms underlying this benefit remain unclear. Virtual reality (VR) exercise may produce distinct autonomic responses compared…
View details →DOI: 10.21203/rs.3.rs-9707388/v1 Negative / Null Result ReportMedicine
Luo X, Zhang H · 2026 · Frontiers in medicine
Objective To assess the impacts of goal-directed sedation nursing intervention on comfort and compliance in children undergoing bronchoalveolar lavage (BAL) under topical anesthesia with procedural sedation. Methods A total of 168 children…
View details →DOI: 10.3389/fmed.2026.1852309 Negative / Null Result ReportMedicine
Chai Y, Shi T, Jiang H et al. · 2026 · Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
Background Fibular allograft (FA) augmentation is proposed to address the lack of medial column support in plate-fixed proximal humeral fractures; however, the role of FA augmentation in these fractures remains inadequately elucidated. Our…
View details →DOI: 10.1186/s10195-026-00934-6 Negative / Null Result ReportMedicine
Kang D, Eun SD, Park J · 2026 · Scientific reports
Stroke survivors living in the community often experience persistent impairments in muscle strength, balance, mobility, and cardiorespiratory fitness after hospital discharge, which increase vulnerability during daily activities. This…
View details →DOI: 10.1038/s41598-026-50927-y Negative / Null Result ReportMedicine
Potluri AS, Yadav AS, Weintraub MT et al. · 2026 · The Journal of arthroplasty
Introduction This multicenter randomized controlled trial (RCT) sought to determine if dual-mobility bearings (DM) reduce dislocations in patients at high-risk for instability undergoing primary total hip arthroplasty (THA) compared to…
View details →DOI: 10.1016/j.arth.2026.06.018 Negative / Null Result ReportMedicine
Jiang Y, Wang Z, Wen H et al. · 2026 · BMC anesthesiology
Background Drug-induced sleep endoscopy (DISE) is widely used to evaluate upper airway obstruction in patients with obstructive sleep apnea syndrome (OSAS). We aimed to compare the sedative efficacy and safety of esketamine combined with…
View details →DOI: 10.1186/s12871-026-03987-6 Negative / Null Result ReportOpen accessMedicine
Wang Y, Li C, Zhang H et al. · 2026 · International journal for equity in health
BACKGROUND: Vision impairment is common among children and is known to affect learning, but its impact on children’s mental health has received less attention, especially in low- and middle-income countries. This study aims to focus on a…
View details →DOI: 10.1186/s12939-026-02854-7 Negative / Null Result ReportMedicine
Darroudi S, Ghazaee H, Babaei N et al. · 2026 · Scientific reports
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has demonstrated cardioprotective effects beyond glycemic control. Empagliflozin has anti-inflammatory and antioxidant effects in long-term administration; however, current…
View details →DOI: 10.1038/s41598-026-44492-7 Negative / Null Result ReportMedicine
Yadav D, Ghuman NK, Kathuria P et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To study the effect of intrauterine instillation of Hyaluronan enriched media on reproductive outcomes of intrauterine insemination treatment. Design and participants 100 couples with unexplained infertility were approached and…
View details →DOI: 10.1016/j.ejogrb.2026.115100 Negative / Null Result ReportOpen accessMedicine
Yan L, Yin H, Shi L et al. · 2026 · Drug design, development and therapy
Purpose To evaluate the efficacy and safety of PHPV in the treatment of persistent high-risk papillomavirus (hrHPV) infection of the cervix. Patients and methods A randomized controlled trial (RCT) was conducted on patients with persistent…
View details →DOI: 10.2147/dddt.s542859 Negative / Null Result ReportMedicine
Zhu F, Sun Y, Kuang D et al. · 2026 · Journal of medical Internet research
Background Children with inattentive attention-deficit/hyperactivity disorder (ADHD) often present with impairments in executive functions and fine motor skills in addition to core inattentive symptoms. However, evidence remains limited…
View details →DOI: 10.2196/97365 Negative / Null Result ReportMedicine
Podoly TY, Even-Ezra H, Doron G · 2025 · Journal of affective disorders
Misophonia is a condition characterized by strong, aversive reactions to specific sounds produced by others, often manifesting as intense negative emotions like anger or rage in response to nearby noises. The present study aimed to…
View details →DOI: 10.1016/j.jad.2025.03.060 Negative / Null Result ReportMedicine
El-Nagdy NK, Mansour NO, Diab AAA et al. · 2025 · Pharmacotherapy
Background Midodrine has been primarily studied as an adjunctive oral therapy to reduce the need for vasopressors in intensive care units (ICU). Nonetheless, the available results evaluating midodrine as an adjuvant therapy in the…
View details →DOI: 10.1002/phar.70018 Negative / Null Result ReportMedicine
van Lennep JPA, van Middendorp H, Leong OV et al. · 2025 · Scandinavian journal of pain
Objectives To understand how different individuals respond to placebo effects, it is relevant to disentangle the influence of someone's personality and genetic variations. The aim of this exploratory study was to investigate the role of…
View details →DOI: 10.1515/sjpain-2025-0029 Negative / Null Result ReportMedicine
Jones N, Humm K, Tinson EW · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial…
View details →DOI: 10.1111/vec.70073 Negative / Null Result ReportOpen accessMedicine
Panzenböck LF, Abdel Nour G, Dürrschnabel DL et al. · 2026 · Global spine journal
Study DesignRandomized controlled trial.ObjectivesTo characterize postoperative C-reactive protein (CRP) trajectories as predictors of surgical site infection (SSI) following lumbar spine surgery, to determine optimal CRP thresholds, and…
View details →DOI: 10.1177/21925682261450878 Negative / Null Result ReportOpen accessMedicine
Pihlaja S, Lipsanen J, Ritola V et al. · 2026 · Frontiers in psychology
Among patients receiving internet-delivered cognitive behavioral therapy (iCBT) for depression in routine clinical practice, 101 patients were randomized to either iCBT as usual or to iCBT with add-on scheduled telephone support (STS).…
View details →DOI: 10.3389/fpsyg.2026.1704049 Negative / Null Result Report
Xiao C, Jing S, Yang G et al. · 2025 · Preprint
Abstract Background Regional anesthesia techniques, including the serratus anterior plane block (SAPB), reduce postoperative pain after minimally invasive cardiac surgery. However, the evidence regarding its impact on transapical…
View details →DOI: 10.21203/rs.3.rs-7828277/v1 Negative / Null Result ReportMedicine
Randy H, Perrin TP, Ghaith A et al. · 2025 · American journal of physiology. Regulatory, integrative and comparative physiology
Aging is associated with cerebrovascular impairment, increasing the risk for neurovascular and degenerative diseases. Intermittent hypoxic conditioning (IHC) has been proposed as a valuable strategy to enhance vascular health. However, its…
View details →DOI: 10.1152/ajpregu.00160.2025 Negative / Null Result Report
Pulliainen H, Kataja E, Löyttyniemi E et al. · 2025 · Preprint
Abstract Background We examined whether an interactive four-dimensional (4D) ultrasound intervention decreases prenatal and early postnatal depressive symptoms and improves maternal-fetal attachment. Methods This randomized controlled…
View details →DOI: 10.21203/rs.3.rs-6672112/v1 Negative / Null Result ReportMedicine
Wakui N, Kawakubo S, Harayama M et al. · 2025 · Journal of the American Pharmacists Association : JAPhA
Background In Japan, human papillomavirus (HPV) vaccination rates remain low, partially owing to safety concerns from media reports. Pharmacies, as accessible health care facilities, often serve as sources of health information. However,…
View details →DOI: 10.1016/j.japh.2025.102901 Negative / Null Result ReportMedicine
Narang BJ, Štritof A, Debevec T · 2025 · International journal of sport nutrition and exercise metabolism
The ergogenic effects of caffeine for endurance performance at sea level are well established. However, whether caffeine enhances exercise capacity or modulates cardiorespiratory responses in hypoxia remains unclear. Twenty-nine healthy,…
View details →DOI: 10.1123/ijsnem.2025-0024 