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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

278 results for "replication" · page 8 of 10

Negative / Null Result ReportMedicine

DNAemia Thresholds to Discontinue Antivirals in Preemptive Management for Cytomegalovirus Seropositive Recipients After Kidney Transplantation.

Miehrig AH, Foresto RD, Tedesco-Silva H et al. · 2026 · Transplantation

Background Treatment of cytomegalovirus (CMV) after kidney transplantation aims to achieve cessation of viral replication; however, the use of highly sensitive DNA assays creates uncertainty regarding the optimal DNAemia threshold for…

View details →DOI: 10.1097/tp.0000000000005695
Negative / Null Result Report

Incidence of SARS-CoV-2 in Patients with Rheumatic Diseases on Hydroxychloroquine, Compared with the Incidence of SARS-CoV-2 in Controls on a Prophylactic Dose of Hydroxychloroquine

Jordhani M, Ruci D, Jordhani P et al. · 2025 · Preprint

Background: Hydroxychloroquine (HCQ) is a disease-modifying antirheumatic drug used in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and other autoimmune diseases. Although HCQ reduces SARS-CoV-2 replication in vitro at…

View details →DOI: 10.20944/preprints202509.1673.v1
Negative / Null Result ReportOpen accessMedicine

Alpha-linolenic acid associations with disability and brain volume in multiple sclerosis: a brief replication report.

Korbmacher M, Myhr KM, Wergeland S et al. · 2026 · Frontiers in neurology

Objective To replicate and extend recent findings, suggesting that higher serum alpha-linolenic acid (ALA) levels are associated with reduced disease activity and progression in multiple sclerosis (MS). Methods We reanalysed clinical trial…

View details →DOI: 10.3389/fneur.2026.1796427
Negative / Null Result Report

Class Composition Effects in Achievement and Interest and the Role of the Learning Environment Revisited: A Conceptual Replication and Extension of Lavrijsen et al. (2022)

Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint

Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…

View details →DOI: 10.31234/osf.io/zkg9r_v1
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Buchanan EM et al. · 2025 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v6
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Balci BB et al. · 2025 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v4
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Balci BB et al. · 2025 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v5
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Balci BB et al. · 2025 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v3
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Buchanan EM et al. · 2025 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v2
Negative / Null Result ReportOpen accessPlant culture

Effect of Increase in Plant Density on Stem Yield and Sucrose Content in Two Sweet Sorghum Cultivars

A Soleymani, A Almodares, A. Naranjani · 2011 · پژوهشهای زراعی ایران

Abstract In order to evaluate the effect of increase plant density on stalk yield and sucrose content in two sweet sorghum cultivars, an experiment was conducted at Research Farm of Isfahan University located at Zaghmar village. A split plot layout within a randomized complete block design with tree replication was used. Main plots were plant densities (100, 200, 300, 400, 500 and 600 thousand plant/ha) and subplots were cultivars (Rio and Keller). The effect of plant density at hard dough harvest stage on plant height, stem diameter, number of tillers, stem fresh weight and juice yield were s

View details →DOI: 10.22067/gsc.v8i3.7761
Negative / Null Result ReportOpen accessMedicine

Replication of null results: Absence of evidence or evidence of absence?

Pawel S, Heyard R, Micheloud C et al. · 2024 · eLife

In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a 'replication success.' Here, we discuss the logical problems with this approach:…

View details →DOI: 10.7554/elife.92311
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by inducing status competition?

Lazarevic LB, Wagge JR, Balci BB et al. · 2023 · Preprint

The present study presents results of a collaborative registered replication of Griskevicius et al.’s (2010) findings from Experiment 1 conducted by 24 student groups from six countries (N = 3,774) investigating if pro-environmental…

View details →DOI: 10.31234/osf.io/sfmz8
Negative / Null Result ReportOpen accessMedicine

WRNexo is not required to maintain normal sex ratios in Drosophila: A CURE-Based Investigation.

Bolterstein E, Mungre S, Nuss K et al. · 2025 · microPublication biology

WRNexo and Blm , Drosophila orthologs of human WRN and BLM RecQ helicases, play crucial roles in DNA replication and repair. Using a Course-based Undergraduate Research Experience (CURE) in an introductory Biology course, we investigated…

View details →DOI: 10.17912/micropub.biology.001620
Abandoned HypothesisOpen accessMedicine

The Bayesian audit: evaluating the proportionality of scientific claims to evidence - a case study on social priming and walking speed.

Costa T · 2026 · Frontiers in psychology

Across psychology, bold empirical claims often outpace the evidential support on which they rest. The replication crisis has shown that statistical significance alone provides little guidance about what should rationally be believed. To…

View details →DOI: 10.3389/fpsyg.2026.1799078
Negative / Null Result Report

Psychotic-like experiences and white matter microstructure: A fixel-based analysis approach with robust replication across two cohorts

Goodwin I, Larsen KM, Sangchooli A et al. · 2025 · Preprint

Structural deficits in white matter fibre have been linked to psychosis. However, it remains unclear whether these aberrations are present in individuals that experience non-clinical psychotic-like experiences, predating illness onset.…

View details →DOI: 10.31234/osf.io/hv596_v1
Negative / Null Result ReportOpen accessMedicine

Psychotic-Like Experiences and White Matter Microstructure: A Fixel-Based Analysis Approach With Robust Replication Across Two Cohorts.

Goodwin I, Larsen KM, Sangchooli A et al. · 2025 · Human brain mapping

Structural deficits in white matter fibre have been linked to psychosis. However, it remains unclear whether these aberrations are present in individuals that experience non-clinical psychotic-like experiences, predating illness onset.…

View details →DOI: 10.1002/hbm.70414
Negative / Null Result Report

Peer Action Coordination in Middle Childhood: A Replication Null Finding on Emotion Understanding and Inhibitory Control

Barresi G, Viana KMP, Hermansen TK et al. · 2025 · Preprint

Peer action coordination in middle childhood is thought to benefit from socio-cognitive abilities such as emotion understanding and inhibitory control, but empirical evidence for their role is limited. This study replicates and extends a…

View details →DOI: 10.20944/preprints202512.0218.v1
Negative / Null Result ReportOpen accessMedicine

Effect of Osteocalcin on Insulin Sensitivity, Insulin Secretion, and β-cell Compensation in Mexican Americans.

Gao Y, Hsu V, Kil A et al. · 2026 · The Journal of clinical endocrinology and metabolism

Context Previous animal studies show association between osteocalcin (OC) and type 2 diabetes-related quantitative traits (QTs), with some suggesting these effects being mediated by adipokines. Replication in humans has been inconsistent.…

View details →DOI: 10.1210/clinem/dgaf460
Negative / Null Result ReportOpen accessBiology

Genetic variation of the mitochondrial D-loop region containing mitochondrial transcription factor A (TFAM) binding sites is not associated with marbling in Wagyu × Limousin F2 crosses

T. Kunej, J. Michal · 2005 · Acta Agriculturae Slovenica

Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is essential for initiation of transcription and replication of mitochondrial DNA (mtDNA). It has been shown that TFAM binds the entire length of the mtDNA, but…

View details →DOI: 10.14720/aas.2005.86.2.15164