459 results in Negative / Null Result Report for "randomized controlled trial" · page 8 of 16
Negative / Null Result ReportMedicine
Keels JN, Babicheva V, McDonald IR et al. · 2026 · Cancers
Background/Objectives : We aimed to test two different visual arrays for helping individuals accurately interpret colorectal cancer risk in Lynch syndrome. We also sought to examine factors associated with intention to share genetic test…
View details →DOI: 10.3390/cancers18091369 Negative / Null Result ReportMedicine
Alhabli I, Ishaque N, Kate M et al. · 2026 · Journal of neurointerventional surgery
Background Thrombus migration can occur in patients receiving IV thrombolysis for acute stroke. This study compared the effects of IV tenecteplase (0.25 mg/kg) versus alteplase (0.9 mg/kg) on thrombus movement in patients undergoing…
View details →DOI: 10.1136/jnis-2025-023336 Negative / Null Result ReportMedicine
Trakarnvanich T, Nochaiwong S, Ruengorn C et al. · 2026 · Scientific reports
To date, little is known regarding the treatment effects of different timed-dosing antihypertensive medications among hypertensive patients with albuminuria. We aimed to investigate whether morning or evening dosing of antihypertensive…
View details →DOI: 10.1038/s41598-026-54798-1 Negative / Null Result ReportMedicine
Maddahi N, Zamani B, Nadjarzadeh A et al. · 2026 · Urology journal
Purpose This study investigated the impact of synbiotics on blood and urinary concentrations of factors related to kidney stone formation in overweight or obese patients with hyperoxaluria. Materials and methods A randomized double-blind…
View details →DOI: 10.22037/uj.v22i.8740 Negative / Null Result ReportMedicine
Caenepeel C, Deleu S, Vazquez Castellanos JF et al. · 2025 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Rigorous donor preselection on microbiota level, strict anaerobic processing, and repeated fecal microbiota transplantation (FMT) administration were hypothesized to improve FMT induction of remission in ulcerative…
View details →DOI: 10.1016/j.cgh.2024.05.017 Negative / Null Result ReportMedicine
Sigaard JVA, Spindler H, Joensen EDR et al. · 2026 · Journal of palliative medicine
Background An estimated 4.4 million people in Europe require palliative care annually, a number expected to rise with population aging. Telepalliative care (TPC) has been practiced in various settings over the past two decades. The Telepal…
View details →DOI: 10.1177/10966218261444643 Negative / Null Result Report
Wongkraisri C, Chusuwanrak K, Laocharoenkeat A et al. · 2024 · Preprint
Abstract Background Hand-foot syndrome (HFS) is a common adverse event of capecitabine causing treatment modifications. Topical urea cream can reduce sorafenib-induced hand-foot skin reaction. However, its benefit in preventing…
View details →DOI: 10.21203/rs.3.rs-4712325/v1 Negative / Null Result ReportOpen accessMedicine
Gam S, Hermann AP, Juhl CB et al. · 2026 · Obesity (Silver Spring, Md.)
Objective This study aimed to investigate whether a single infusion of 5 mg zoledronic acid, given before bariatric surgery to prevent bone loss, could also hinder the loss of muscle mass, strength, and physical function. Methods In this…
View details →DOI: 10.1002/oby.70062 Negative / Null Result ReportOpen accessMedicine
Comboni LM, Glover ES, Napolitano SC et al. · 2026 · Foods (Basel, Switzerland)
We assessed whether consuming UV light-exposed mushrooms (UVMs) would offset the seasonal decline in circulating total 25-hydroxyvitamin D (25OHD), an index of vitamin D status. During late fall and winter, 41 adults (19 M/22 F, age 43 ±…
View details →DOI: 10.3390/foods15091572 Negative / Null Result ReportOpen accessMedicine
Cao Y, Li Q, Guo W et al. · 2025 · Frontiers in immunology
To evaluate the efficacy of COVID-19 convalescent plasma (CCP) in preventing SARS-CoV-2 infection in hematopoietic stem cell transplantation (HSCT) recipients during the early post-transplant period, a single-center, randomized controlled…
View details →DOI: 10.3389/fimmu.2025.1626775 Negative / Null Result ReportMedicine
Yurttutan S, Geçkil E · 2026 · Journal of pediatric nursing
Aim This study aimed to evaluate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on depression, anxiety, stress, and hopelessness among parents of children with autism (Autism Spectrum Disorder [ASD]). Method A…
View details →DOI: 10.1016/j.pedn.2026.05.008 Negative / Null Result Report
Kröber P, Wolf F, Saliger J et al. · 2026 · Preprint
Background Gait training incorporating visual feedback or rhythmic auditory cueing has shown promising results in neurological conditions but has rarely been investigated in clinical rehabilitation for persons with Multiple Sclerosis…
View details →DOI: 10.64898/2026.06.18.26356023 Negative / Null Result ReportMedicine
Yılmaz NA, Caner İ · 2026 · BMC medical education
Innovative educational strategies are increasingly needed in physiotherapy education to support students' learning and professional development. Game-based learning (GBL) is an interactive, student-centered approach that may enhance…
View details →DOI: 10.1186/s12909-026-09782-8 Negative / Null Result ReportMedicine
Fiszdon JM, Wang K, Fulford D et al. · 2026 · Journal of the International Neuropsychological Society : JINS
Objectives Poor social function in people with psychosis has been linked to impairments in social cognition and neurocognition, which in turn have been identified as promising treatment targets. We developed a novel social cognitive…
View details →DOI: 10.1017/s1355617726102070 Negative / Null Result ReportOpen accessMedicine
Hostrup M, Jessen S, Tischer SG et al. · 2026 · Scandinavian journal of medicine & science in sports
Misuse of beta 2 -agonists to promote leanness is increasingly reported among young men undertaking resistance training. However, preclinical models demonstrate adverse cardiac remodeling with high-dose beta 2 -agonist. We investigated…
View details →DOI: 10.1111/sms.70302 Negative / Null Result ReportMedicine
Agarwal R · 2026 · American journal of hypertension
Background The mechanism of hypertension associated with erythropoiesis-stimulating agents in chronic kidney disease (CKD) is complex and remains poorly understood. Methods Here, anemic hypertensive patients with CKD and well-controlled or…
View details →DOI: 10.1093/ajh/hpaf200 Negative / Null Result ReportMedicine
Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine
Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…
View details →DOI: 10.1016/j.accpm.2026.101818 Negative / Null Result ReportMedicine
Kaş Alay G, Mutlu B · 2026 · Games for health journal
Objective To determine the effect of training children with familial Mediterranean fever (FMF) using a mobile game (MG) or training booklet (TB) on self-efficacy, symptom management, and quality of life (HRQoL) compared with a control…
View details →DOI: 10.1177/2161783x251414694 Negative / Null Result ReportMedicine
Kolachena V, Priyadarshi M, Singh P et al. · 2026 · Resuscitation
The optimum site of tactile stimulation (TS) during initial steps of neonatal resuscitation in the delivery room (DR) is not well-established. To compare the impact of three different sites of TS (back rub, trunk rub, and sole rub) on…
View details →DOI: 10.1016/j.resuscitation.2026.111190 Negative / Null Result Report
Lee Y, Vazou S, Kim S et al. · 2026 · Preprint
Abstract Exercise is an established strategy for reducing depressive symptoms, yet the psychophysiological mechanisms underlying this benefit remain unclear. Virtual reality (VR) exercise may produce distinct autonomic responses compared…
View details →DOI: 10.21203/rs.3.rs-9707388/v1 Negative / Null Result ReportMedicine
Luo X, Zhang H · 2026 · Frontiers in medicine
Objective To assess the impacts of goal-directed sedation nursing intervention on comfort and compliance in children undergoing bronchoalveolar lavage (BAL) under topical anesthesia with procedural sedation. Methods A total of 168 children…
View details →DOI: 10.3389/fmed.2026.1852309 Negative / Null Result ReportMedicine
Chai Y, Shi T, Jiang H et al. · 2026 · Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
Background Fibular allograft (FA) augmentation is proposed to address the lack of medial column support in plate-fixed proximal humeral fractures; however, the role of FA augmentation in these fractures remains inadequately elucidated. Our…
View details →DOI: 10.1186/s10195-026-00934-6 Negative / Null Result ReportMedicine
Kang D, Eun SD, Park J · 2026 · Scientific reports
Stroke survivors living in the community often experience persistent impairments in muscle strength, balance, mobility, and cardiorespiratory fitness after hospital discharge, which increase vulnerability during daily activities. This…
View details →DOI: 10.1038/s41598-026-50927-y Negative / Null Result ReportMedicine
Potluri AS, Yadav AS, Weintraub MT et al. · 2026 · The Journal of arthroplasty
Introduction This multicenter randomized controlled trial (RCT) sought to determine if dual-mobility bearings (DM) reduce dislocations in patients at high-risk for instability undergoing primary total hip arthroplasty (THA) compared to…
View details →DOI: 10.1016/j.arth.2026.06.018 Negative / Null Result ReportMedicine
Jiang Y, Wang Z, Wen H et al. · 2026 · BMC anesthesiology
Background Drug-induced sleep endoscopy (DISE) is widely used to evaluate upper airway obstruction in patients with obstructive sleep apnea syndrome (OSAS). We aimed to compare the sedative efficacy and safety of esketamine combined with…
View details →DOI: 10.1186/s12871-026-03987-6 Negative / Null Result ReportOpen accessMedicine
Wang Y, Li C, Zhang H et al. · 2026 · International journal for equity in health
BACKGROUND: Vision impairment is common among children and is known to affect learning, but its impact on children’s mental health has received less attention, especially in low- and middle-income countries. This study aims to focus on a…
View details →DOI: 10.1186/s12939-026-02854-7 Negative / Null Result ReportMedicine
Darroudi S, Ghazaee H, Babaei N et al. · 2026 · Scientific reports
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has demonstrated cardioprotective effects beyond glycemic control. Empagliflozin has anti-inflammatory and antioxidant effects in long-term administration; however, current…
View details →DOI: 10.1038/s41598-026-44492-7 Negative / Null Result ReportMedicine
Yadav D, Ghuman NK, Kathuria P et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To study the effect of intrauterine instillation of Hyaluronan enriched media on reproductive outcomes of intrauterine insemination treatment. Design and participants 100 couples with unexplained infertility were approached and…
View details →DOI: 10.1016/j.ejogrb.2026.115100 Negative / Null Result ReportOpen accessMedicine
Yan L, Yin H, Shi L et al. · 2026 · Drug design, development and therapy
Purpose To evaluate the efficacy and safety of PHPV in the treatment of persistent high-risk papillomavirus (hrHPV) infection of the cervix. Patients and methods A randomized controlled trial (RCT) was conducted on patients with persistent…
View details →DOI: 10.2147/dddt.s542859 Negative / Null Result ReportMedicine
Zhu F, Sun Y, Kuang D et al. · 2026 · Journal of medical Internet research
Background Children with inattentive attention-deficit/hyperactivity disorder (ADHD) often present with impairments in executive functions and fine motor skills in addition to core inattentive symptoms. However, evidence remains limited…
View details →DOI: 10.2196/97365 