Negative / Null Result ReportOpen accessComputer Science
Andrea Espis, Chiara Marzi, Stefano Diciotti · 2025 · Scientific Reports
Self-supervised learning (SSL) in computer vision has shown its potential to reduce reliance on labeled data. However, most studies focused on balanced, large, broad-domain datasets like ImageNet, whereas, in real-world medical applications, dataset size is typically limited. This study compares the performance of SSL versus supervised learning (SL) on small, imbalanced medical imaging datasets. We experimented with four binary classification tasks: age prediction and diagnosis of Alzheimer's disease from brain magnetic resonance imaging scans, pneumonia from chest radiograms, and retinal dise
View details →DOI: 10.1038/s41598-025-99000-0Cited by 9 Negative / Null Result ReportOpen accessMedicine
F Visalli, Matteo Capobianco, F. Cappellani et al. · 2026 · International Journal of Molecular Sciences
Mitochondrial dysfunction represents a central hallmark of aging and a broad spectrum of chronic diseases, ranging from metabolic to neurodegenerative and ocular disorders. Nicotinamide riboside (NR), a vitamin B3 derivative and efficient precursor of NAD+ (nicotinamide adenine dinucleotide), and berberine (BBR), an isoquinoline alkaloid widely investigated in metabolic regulation, have independently emerged as promising mitochondrial modulators. NR enhances cellular NAD+ pools, thereby activating sirtuin-dependent pathways, stimulating PGC-1α–mediated mitochondrial biogenesis, and triggering
View details →DOI: 10.3390/ijms27010485Cited by 9 Negative / Null Result ReportOpen accessMedicine
Gustavo Jimenez‐Maggiora, Arndt‐Peter Schulz, Michael Donohue et al. · 2024 · The Journal of Prevention of Alzheimer s Disease
BACKGROUND: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN) studies were conducted between 2014 and 2023, with enrollment completed in 2017 and final study results reported in 2023. The study screening process involved the collection of initial clinical, cognitive, neuroimaging, and genetic measures to determine eligibility. Once randomized, enrolled participants were assessed every four weeks over a 4.5-year follow-up period during which longitudinal clinical, cognitive, and neuroimaging measures wer
View details →DOI: 10.14283/jpad.2024.120Cited by 9 Negative / Null Result Report
Oumaima Alaika, Souad Jamai, Nawal Doghmi et al. · 2020 · Journal of the Saudi Heart Association
Objectives: Speckle-tracking imaging is a novel method for assessing left ventricular (LV) function and ischemic changes. The aim of this prospective study was to assess the diagnostic accuracy of global longitudinal strain (GLS) and…
View details →DOI: 10.37616/2212-5043.1096Cited by 8 Negative / Null Result Report
Richard Lu, Vu Tran Hoang, Wing-Keung Wong · 2020 · Studies in Economics and Finance
Purpose The literature has demonstrated that lump-sum (LS) outperforms dollar-cost averaging (DCA) in uptrend markets while DCA outperforms LS only when the asset price is mean-reverted or downtrend. To bridge the gap in the literature,…
View details →DOI: 10.1108/sef-04-2018-0107Cited by 7 Negative / Null Result Report
Neng Shen, Jing Zhang, Yangchun Cao · 2024 · Business Process Management Journal
Purpose In the context of open innovation, more and more enterprises are leveraging innovation networks to drive disruptive innovation performance, but there is no consensus on the relationship between network embeddedness and enterprise…
View details →DOI: 10.1108/bpmj-03-2024-0191Cited by 6 Negative / Null Result Report
Patrick Albers, Jacob Bennett, Moira Evans et al. · 2024 · Canadian Urological Association Journal
Introduction: Despite a negative magnetic resonance imaging (MRI), some patients may still harbor clinically significant prostate cancer (csPCa, Gleason grade group ≥2). High-resolution micro-ultrasound (microUS) is a novel imaging…
View details →DOI: 10.5489/cuaj.8626Cited by 6 Negative / Null Result Report
Fei Ke, Renbao Wang, Zihao Wang et al. · 2022 · Viruses
As nucleocytoplasmic large DNA viruses, replication of ranaviruses (genus Ranavirus, family Iridoviridae) involves a series of viral and host proteins. We have described that the replication and transcription machinery of Andrias…
View details →DOI: 10.3390/v14050952Cited by 6 Negative / Null Result Report
Sarah Ingber, Rita Selby, Jacques Lee et al. · 2014 · CJEM
ABSTRACT Introduction: Venous thromboembolism (VTE) is difficult to diagnose yet potentially life threatening. A low-risk pretest probability (PTP) assessment combined with a negative Ddimer can rule out VTE in two-thirds of outpatients,…
View details →DOI: 10.2310/8000.2013.130986Cited by 6 Negative / Null Result Report
Robert Philibert, Man-Kit Lei, Mei Ling Ong et al. · 2024 · Genes
The reliability of the associations of the acceleration of epigenetic aging (EA) indices with clinical phenotypes other than for smoking and drinking is poorly understood. Furthermore, the majority of clinical phenotyping studies have been…
View details →DOI: 10.3390/genes15070869Cited by 5 Negative / Null Result Report
Sara Ortiz-Toquero, Francisco J. Muñoz-Negrete, Gema Rebolleda · 2020 · Journal of Neuro-Ophthalmology
Background: Optic disc drusen (ODD) are a dynamic phenomenon, and their appearance, size, and relative location may change. The purpose of this study is to evaluate and quantify the longitudinal changes of buried ODD with enhanced depth…
View details →DOI: 10.1097/wno.0000000000001103Cited by 5 Negative / Null Result Report
Taisaku Ogawa, Koji Ochiai, Tomoharu Iwata et al. · 2022 · PLOS ONE
Developments in high-throughput microscopy have made it possible to collect huge amounts of cell image data that are difficult to analyse manually. Machine learning (e.g., deep learning) is often employed to automate the extraction of…
View details →DOI: 10.1371/journal.pone.0262397Cited by 4 Negative / Null Result Report
James Wan, Raafat Saade, Ling Wang · 2019 · Journal of Organizational Change Management
Purpose A consequence of the UN general assembly resolution calling for increased efficiency and better utilization of resources in all its agencies, is a mandate for change. As a response to this resolution, the purpose of this paper is…
View details →DOI: 10.1108/jocm-10-2018-0288Cited by 3 Negative / Null Result Report
Vidhu Anand, Christopher G. Scott, Khaled Ali et al. · 2025 · Journal of the American Heart Association
Background Tricuspid valve surgery is recommended for severe isolated tricuspid regurgitation (TR) if symptoms persist despite optimal medical therapy. The definition of optimal therapy for TR is unclear beyond managing underlying…
View details →DOI: 10.1161/jaha.124.039989Cited by 2 Negative / Null Result Report
TIMOTHY P. CANAVAN · 2017 · Clinical Obstetrics & Gynecology
Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a…
View details →DOI: 10.1097/grf.0000000000000301Cited by 2 Negative / Null Result Report
Paul Hockings, Kianoush Makvandi, Johannes Hulthe et al. · 2023 · Nephrology Dialysis Transplantation
Abstract Background and Aims We recently showed that comprehensive non-contrast multiparametric Magnetic Resonance Imaging (mpMRI) allowed functional and structural assessment of diabetic kidney disease (DKD) and that an imaging endpoint,…
View details →DOI: 10.1093/ndt/gfad063c_4204Cited by 1 Negative / Null Result Report
Jacob H Schmidt, Bianca Hutton Chimes · 2023 · Journal of Applied Finance & Banking
Abstract Why are there so few women in finance and even fewer managing funds? There is a major discrepancy between the number of female and male fund managers worldwide. The aim of this paper is to ascertain if gender is a contributing…
View details →DOI: 10.47260/jafb/1352Cited by 1 Negative / Null Result Report
Betty Wang, Stacey Broomfield, Anaïs Medina Martín et al. · 2022 · Canadian Urological Association Journal
Introduction: High-resolution micro-ultrasound (microUS) is a novel imaging technique that may visualize clinically significant prostate cancer (csPCa), including those missed by magnetic resonance imaging (MRI), in real-time during…
View details →DOI: 10.5489/cuaj.8094Cited by 1 Negative / Null Result Report
Andreas Plate, Stefania Di Gangi, Christian Garzoni et al. · 2024 · Scientific Reports
Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in…
View details →DOI: 10.1038/s41598-024-55166-7Cited by 1 Negative / Null Result Report
Nicola Arrighi, Alessandro Antonelli, Tiziano Zanotelli et al. · 2011 · Urologia Journal
Objectives During the last 3 decades ultrasonographic and cross-sectional imaging techniques have been widely adopted in the pre-operative staging of renal masses with a progressive technological refinement. The aim of this study is to…
View details →DOI: 10.5301/ru.2011.8521Cited by 1 Negative / Null Result Report
Gemma Massetti, Carlotta Lega, Zaira Cattaneo et al. · 2022 · Brain Sciences
Humans are the only species capable of experiencing pleasure from esthetic stimuli, such as art and music. Neuroimaging evidence suggests that the left dorsolateral prefrontal cortex (DLPFC) plays a critical role in esthetic judgments,…
View details →DOI: 10.3390/brainsci12040467Cited by 1 Negative / Null Result Report
Yasmina Bouzidi, Emmanuel Barteau, Julien Lejeune et al. · 2019 · The Neuroradiology Journal
Background Magnetic resonance imaging (MRI) with a gadolinium injection is currently used in the follow-up of children in remission of cerebral tumors (CTs). Intracerebral gadolinium deposition has been recently reported with unknown…
View details →DOI: 10.1177/1971400919845619Cited by 1 Negative / Null Result ReportMedicine
Mahdavi Sabet, Zeinalkhani, Forghani et al. · 2026 · International journal of breast cancer
This study is aimed at investigating the correlation between apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging (DWI) and prognostic factors in breast cancer. We hypothesized that lower ADC values would be…
View details →DOI: 10.1155/ijbc/5114852 Negative / Null Result ReportMedicine
Darrah, Spence · 2026 · American journal of veterinary research
To compare the proportion of lesions identified on cervical MRI in dogs based on weight. Medical records from a tertiary referral hospital were reviewed for dogs that underwent cervical MRI to investigate clinical signs consistent with…
View details →DOI: 10.2460/ajvr.25.12.0450 Negative / Null Result ReportMedicine
Chittamuru, Vengamma, Priya et al. · 2026 · Journal of maxillofacial and oral surgery
During the second wave of COVID-19 pandemic, there was surge in reporting of COVID-19-associated mucormycosis cases. Government of India declared rhino-orbito-cerebral mucormycosis as a notifiable disease. Managing this condition posed a…
View details →DOI: 10.1007/s12663-024-02120-9 Negative / Null Result ReportMedicine
Kannikeswaran, Sivaswamy, Przyklenk et al. · 2026 · Pediatric neurology
Although not routinely recommended, computed tomography (CT) head are frequently performed in children presenting to emergency department (ED) with seizures. Racial and ethnic disparities have been reported in pediatric ED imaging. Our…
View details →DOI: 10.1016/j.pediatrneurol.2026.05.005 Negative / Null Result ReportMedicine
Liu, Xu, Zhong et al. · 2026 · Quantitative imaging in medicine and surgery
Intracranial atherosclerosis is the predominant etiology of ischemic stroke in East Asian populations. Atherosclerotic progression frequently involves concomitant vascular remodeling, and stroke risk profiles may vary across distinct…
View details →DOI: 10.21037/qims-2025-1812 Negative / Null Result ReportMedicine
Ciacciarelli, Nicolini, Saia et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Infarct growth rate (IGR) is highly heterogeneous among ischemic stroke patients, reflecting a spectrum of progressor phenotypes with clinical implications. We aim to compare different imaging approaches to investigate stroke progressors…
View details →DOI: 10.1007/s10072-026-09148-4 Negative / Null Result ReportMedicine
Panwar, Amiri-Kazaz, Szczepaniec · 2026 · Environmental entomology
Amauromyza karli Hendel (Diptera: Agromyzidae) has recently emerged as a damaging stem-boring pest of quinoa in Colorado and other quinoa-producing regions of the United States. Severe infestations have been associated with substantial…
View details →DOI: 10.1093/ee/nvag069 Negative / Null Result ReportMedicine
Lin, Li, Cheng et al. · 2026 · Briefings in bioinformatics
Current metabolomics approaches predominantly rely on group-level differential abundance screening. While effective for identifying biomarkers, this paradigm often overlooks upstream regulatory hubs and fails to resolve the…
View details →DOI: 10.1093/bib/bbag264 