A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
1761 results in Negative / Null Result Report for "Mpro" · page 54 of 59
Du, Zhang, Xu et al. · 2026 · Scientific reports
To evaluate the remediation strategies for newly reclaimed, heavily salinized farmland in Xinjiang province, China, a three-year field experiment was conducted comparing different treatments, such as agricultural improvement measures…
Baudin, Pouyau, Subtil et al. · 2026 · JAMA
Prone positioning has been shown to improve respiratory mechanics and oxygenation, but its clinical benefit in infants with acute viral bronchiolitis receiving high-flow nasal cannula (HFNC) support remains unknown. To investigate whether…
Tasgaonkar, Rathi, Agrawal et al. · 2026 · International journal of clinical pediatric dentistry
Preserving primary teeth with crowns is vital in pediatric dentistry, especially for those compromised by dental caries, previous treatments, or malformations. To address the limitations of traditional esthetic crowns, Bioflx crowns have…
Parirokh, Manochehrifar, Nakahee et al. · 2026 · Iranian endodontic journal
The close relationship between pulp stones in the pulp chamber and pulp neurovascular tissues suggests that the presence of pulp stones may compromise successful anesthesia. The present study assessed the effect of pulp stone presence on…
Lahaye, Haegdorens, Franck et al. · 2026 · European geriatric medicine
To evaluate the effectiveness of a structured, team-delivered intervention based on cognitive behavioural therapy for insomnia (CBT-I) on sleep and related outcomes in nursing home residents. A cluster randomised controlled trial with…
Ziltzer, Bulbul, Barry et al. · 2026 · The Laryngoscope
To investigate whether routine involvement of the medical hospitalist service (MHS) in postoperative medical management of head and neck cancer (HNC) patients undergoing major ablative head and neck surgery with free tissue transfer (FTT)…
Abelovska, Malinova, Sucha et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
This pilot study evaluated "Your Health Belongs to You," a six-week group intervention combining psychotherapy and exercise to improve quality of life, emotional health, and symptom management in individuals with Multiple Sclerosis (MS),…
Bakhshalipoor, Bolandi, Nahidi et al. · 2026 · Scientific reports
This study evaluated the effects of double nanoemulsions of saffron petal extract (DN-SPE), stabilized with soybean (SPI) and pea protein isolates (PPI), alone or combined with Lepidium sativum L. seed gum (LSG) (SL or PL), on the quality…
Wang, Li, Zhang et al. · 2026 · Child development
This study examines how center-based parenting interventions aimed at improving early child development in rural China affect the mental health of caregivers. Data from an analytic sample of 615 caregiver-child dyads (children aged 6 to 24…
Eminoğlu · 2026 · Food science & nutrition
In this study, yogurt formulations with paraprobiotic (heat inactivated Lactobacillus acidophilus ) and postbiotic (autolyzed and dried Saccharomyces cerevisiae ) additions were developed to improve the techno-functional properties of…
Partlova, Comley, Haigh et al. · 2026 · Experimental neurology
Spinal muscular atrophy (SMA) is characterized by motor neuron loss and neuromuscular junction (NMJ) pathology. Although SMN-upregulating therapies such as Nusinersen markedly improve survival and motor function for many patients,…
Shalamov, Cromwell, Guha · 2026 · AJP reports
Background: Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder that causes alveolar hypoventilation because of impaired chemoreceptor response to hypercapnia and hypoxia occurring due to a dysfunctional central…
Su, Huang, Wang · 2026 · SLAS technology
The accumulation of pathological bronchial secretions compromises ventilation and oxygenation in critically ill patients and may lead to atelectasis or secondary infection in severe cases, making timely identification and removal of…
Bonglack, Carrel-Lammert, Hoehn et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Acute urinary tract infections (UTIs) are common after prolapse and anti-incontinence surgery, with incidence rates varying from 14% to 64%. The objective was to decrease rates of symptomatic urinary tract infections in patients undergoing…
Serttas, Uysal, Deği̇rmenci̇ et al. · 2026 · Injury
Urinary tract infection(UTI) is a common complication following hip fracture surgery in elderly patients. Urinary catheterization is frequently used to improve patient comfort during prolonged preoperative immobilization; however, its…
Vu, Nguyen, Nguyen et al. · 2026 · Substance use & misuse
Patient trust in healthcare providers (PTP) is critical for improving treatment adherence and outcomes in substance use disorders. As concurrent opioid and methamphetamine use increasingly complicates methadone maintenance treatment (MMT),…
Oletu, Oladimeji, Osueni et al. · 2026 · Cureus
Intensive care unit (ICU) survivors experience high rates of healthcare utilization after hospital discharge, including readmissions and emergency department (ED) visits. Timely outpatient follow-up has been proposed to improve care…
Mantovani, Chagas, Horiquini-Barbosa · 2026 · Developmental neurorehabilitation
Children diagnosed with central nervous system (CNS) tumors frequently present with persistent motor impairments that compromise independence and participation. Although the Gross Motor Function Measure (GMFM-88) is widely used in…
Yao, Mamone, Wu et al. · 2026 · Frontiers in psychology
Age-related declines in muscle strength are partly attributable to altered neural drive and agonist-antagonist coordination. This study aimed to evaluate the effects of motor imagery training (MIT) on maximal force production and…
Huang, Tsai, Lin et al. · 2026 · Taiwanese journal of obstetrics & gynecology
A higher oocyte yield is generally associated with improved outcomes in assisted reproductive technology (ART). Vitrification enables the accumulation of oocytes, zygotes, or embryos across multiple cycles, offering a potential strategy to…
Prajapati, Gupta, Mathew et al. · 2026 · The Indian journal of tuberculosis
Tuberculosis (TB) is a significant health issue in the world, and lack of health literacy has resulted in delayed care-seeking practices, non-compliance with treatment regimens, and subsequent stigma in communities with the infection. The…
Riyapan, Laopran, Chantanakomes et al. · 2026 · Resuscitation
Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) has been shown to increase bystander CPR rates and improve outcomes after out-of-hospital cardiac arrest (OHCA). However, dispatchers cannot directly visualize the scene, which may…
Trevethan, Doig, Patterson et al. · 2026 · Lymphology
ICG lymphography is a lymphatic imaging tool that can inform lymphedema treatment, including self-management. Self-management requires patient engagement in a multimodal treatment program. However, lack of knowledge about lymphedema,…
Zhang, Jiang, Jiang · 2026 · The journal of sexual medicine
Hypertension is a major cause of erectile dysfunction (ED). The impact of hypertension on the transcriptome and proteome of penile corpus cavernosum tissue, as well as its relationship with erectile dysfunction, is not clear. This study…
Tsiotsios, Vamvakas, Labropoulou et al. · 2026 · Acta haematologica
Introduction Patients with homozygous β-thalassemia show continuously improved survival, which has contributed to the development of kidney complications, predominantly expressed as increased albuminuria. In particular, patients with…
Ani, Hameed · 2026 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
Aim: This study aimed to evaluate the effectiveness of a structured intravenous infusion protocol in improving the quality of care and reducing IV-related complications among hospitalized patients. Materials and Methods: A purposive sample…
Chilundo, Xinavane, Huo et al. · 2026 · Frontiers in reproductive health
Despite national policies promoting adolescent- and youth-friendly health services, implementation gaps hinder improvements in adolescent sexual and reproductive health outcomes in Mozambique. S-NICE is a structured, participatory…
Sheikh, Singh, Smith et al. · 2026 · Frontiers in cardiovascular medicine
The impact of catheter-directed thrombolysis (CDT), catheter-directed embolectomy (CDE) and surgical pulmonary embolectomy (SPE) on long term RV function among patients with acute PE remains unclear. We investigated the association of…
Navidifar, Kaveh, Hosseini et al. · 2026 · Veterinary and animal science
Efficient estrus synchronization is important for improving reproductive performance in dairy herds; however, variations in ovarian activity among cows of different parities may influence responses to synchronization protocols. The present…
Li H, Li X, Gao W et al. · 2026 · Frontiers in sports and active living
Background Basketball requires players to perform complex technical actions under conditions of dynamic instability. Traditional stability and strength training mainly improves muscle strength; however, it is often insufficient for…