Negative / Null Result ReportMedicine
Kavakli, Bozkurt, Diri et al. · 2026 · Surgical endoscopy
Conventional abdominal wall blocks primarily target somatic afferent nerves and may therefore provide limited relief for the peritoneal component of postoperative pain. This study aimed to investigate whether a laparoscopic-guided deep…
View details →DOI: 10.1007/s00464-026-12973-5 Methods Dead-EndMedicine
Kadesch, Weiss, Hetjens et al. · 2026 · Obesity surgery
Preoperative multidisciplinary team assessment (MTA) for bariatric surgery is complex and associated with high attrition rates. Digital health applications may improve patient engagement and completion rates, but evidence remains limited.…
View details →DOI: 10.1007/s11695-026-08768-1 Negative / Null Result ReportMedicine
Coellar, Keshvani, Jain et al. · 2026 · American journal of preventive cardiology
Medication non-adherence following acute coronary syndrome (ACS) is common, especially among underserved populations. The use of fixed-dose combination pills (polypills) may improve both adherence and prescription practices. This…
View details →DOI: 10.1016/j.ajpc.2026.101499 Negative / Null Result ReportMedicine
Fukushi, Emori, Tsuchie et al. · 2026 · Cureus
Aggressive surgical resection with adequate margins is associated with improved local control and survival in selected patients with primary spinal sarcomas. However, anatomical constraints often preclude complete resection, and outcomes…
View details →DOI: 10.7759/cureus.108569 Negative / Null Result ReportMedicine
Merluzzi, Lepri, Lidano et al. · 2026 · Animals : an open access journal from MDPI
The Anatomage Table Vet (ATV) is a digital tool that may facilitate the understanding of complex structures and improve visuospatial skills. This study evaluated the effectiveness of the ATV as a review method prior to cadaveric dissection…
View details →DOI: 10.3390/ani16111695 Negative / Null Result ReportMedicine
Chen, Yi, Cao et al. · 2026 · Neurology
The efficacy of endovascular treatment for acute large vessel occlusion strokes has been demonstrated, but whether it can improve functional outcomes in patients with acute ischemic stroke (AIS) who only present with severe large vessel…
View details →DOI: 10.1212/wnl.0000000000218157 Negative / Null Result ReportMedicine
Zhang, Chen, Chen et al. · 2026 · Chinese medical journal
This is a multicenter, randomized, double-blind, placebo-controlled interventional clinical study to evaluate the efficacy and safety of pronase in improving visibility in colonoscopy and to evaluate whether pronase can increase the…
View details →DOI: 10.1097/cm9.0000000000004114 Negative / Null Result ReportMedicine
Budak, Yıldırım · 2026 · Psychiatria Danubina
Treatment adherence improves the quality of life and functional outcomes in patients with bipolar disorder (BD) by supporting effective disease management and fostering the development of self-esteem and self-efficacy. This study aimed to…
View details →DOI: 10.24869/psyd.2026.68 Negative / Null Result ReportMedicine
Bagdonas, Schäfer, Wolf et al. · 2026 · BMC complementary medicine and therapies
Complementary and alternative medicine (CAM) is widely used by oncology patients to manage symptoms, reduce stress, and improve quality of life. Unlike conventional treatments, CAM is rarely reimbursed in Germany, resulting in significant…
View details →DOI: 10.1186/s12906-026-05417-z Negative / Null Result ReportMedicine
Ran, Wei, Huang et al. · 2025 · Frontiers in psychology
To investigate the effectiveness of a VR preoperative education program with sensory information support in reducing perioperative anxiety and improving the delivery experience among primiparas undergoing cesarean section (CS). A total of…
View details →DOI: 10.3389/fpsyg.2025.1648706 Negative / Null Result ReportMedicine
Sumi, Yasutaka, Ogata et al. · 2026 · Gan to kagaku ryoho. Cancer & chemotherapy
Hematologic malignancies have shown improved prognosis in some diseases owing to advanced treatment. Cytarabine (Ara-C) is widely used for treatment; however, ocular symptoms frequently occur as a side effect. In this retrospective study,…
Negative / Null Result ReportMedicine
Yang, Dong, Cheng et al. · 2026 · Clinical oral investigations
To evaluate whether early orthodontic traction of inversely impacted maxillary central incisors with curved roots affects subsequent root development and labial/palatal alveolar bone support. A retrospective cone-beam computed tomography…
View details →DOI: 10.1007/s00784-026-06962-0 Negative / Null Result ReportMedicine
Lee, Mak, Leong et al. · 2026 · European journal of clinical nutrition
Okara is a protein-rich food by-product that can be biovalorised with Rhizopus oligosporus to improve its protein digestibility and quality. This study investigated postprandial circulating amino acid changes following okara and…
View details →DOI: 10.1038/s41430-026-01769-4 Negative / Null Result ReportMedicine
Hamadani, Banu, Wieczorek et al. · 2026 · Scientific reports
A soft-anchored titanium (Ti-6Al-4V) mesh implantable device was designed and morphologically characterised in an in vitro study. The mesh implant consists of a titanium mesh aimed at preserving continence and improving the quality of life…
View details →DOI: 10.1038/s41598-026-46836-9 Negative / Null Result ReportMedicine
Lasmanovich, Chepeliuk, Fihman et al. · 2026 · World journal of surgical oncology
Segmental ureterectomy (SU) is an established kidney-sparing strategy for upper tract urothelial carcinoma (UTUC), yet few studies have compared the standard open approach to the emerging robotic modality. We performed a clinical outcome…
View details →DOI: 10.1186/s12957-026-04422-3 Negative / Null Result ReportMedicine
Berthelot, Audureau, Bouleti et al. · 2026 · Archives of cardiovascular diseases
The MonCœur smartphone application (app) was developed to meet the specific needs of individuals living with heart failure (HF). To evaluate whether the MonCœur smartphone app improves self-care at 6months in patients with HF,…
View details →DOI: 10.1016/j.acvd.2026.04.007 Negative / Null Result ReportMedicine
Wilcox, Campbell, Gill et al. · 2026 · The bone & joint journal
Computer navigation is capable of improving the accuracy of glenoid baseplate and screw positioning in shoulder arthroplasty, but there is very limited evidence of its effect on clinical outcomes. In Australia, there is one commonly used…
View details →DOI: 10.1302/0301-620x.108b6.bjj-2025-1772.r1 Negative / Null Result ReportMedicine
Sood, Turnbull, De Silva et al. · 2026 · Heart, lung & circulation
Improved patient outcomes after ventricular arrhythmia (VA) ablation procedure have been found to correlate with procedures being performed in high volume centres. Whether the concentration of expertise in experienced, urban centres…
View details →DOI: 10.1016/j.hlc.2025.12.026 Negative / Null Result ReportMedicine
Esmer, Hafızoğlu, Bardakçı et al. · 2026 · Journal of ovarian research
Advanced epithelial ovarian cancer (EOC) is commonly diagnosed at late stages, and despite improvements with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS), prognosis remains poor. Body composition has emerged…
View details →DOI: 10.1186/s13048-025-01960-4 Negative / Null Result ReportMedicine
Li, Zhan, Zhang et al. · 2026 · Molecules (Basel, Switzerland)
The present study investigates the effect of 1,8-cineole on improving lipid metabolism disorder by regulating oxidative stress and inflammation via the TLR4/MyD88/NF-κB pathway. 1,8-Cineole is a monoterpene compound widely found in…
View details →DOI: 10.3390/molecules31111933 Negative / Null Result ReportMedicine
Rovira-Lastra, ElOtmani-Sabiri, Ustrell-Barral et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : This clinical study assessed the validity of articulating paper for detecting occlusal contacts points, including examining the effects of clinical technique, paper thickness, and the arch. Methods : This…
View details →DOI: 10.3390/diagnostics16101450 Negative / Null Result ReportMedicine
Chen, Ma, Zhang · 2026 · Accident; analysis and prevention
Automated vehicles (AVs) are designed to improve traffic safety, mobility, and driver comfort; however, their benefits depend on the widespread adoption of AVs. As full market penetration remains unlikely in the near term, AVs will…
View details →DOI: 10.1016/j.aap.2026.108516 Negative / Null Result ReportMedicine
Pujol, Minguell, Pijoan et al. · 2025 · Journal of orthopaedics
To determine if maintaining the preoperative CPAK class influences on clinical outcomes when performing a functional aligned robotic assisted TKA (RATKA). This prospective cohort study compared patients who maintained their preoperative…
View details →DOI: 10.1016/j.jor.2025.06.030 Methods Dead-EndMedicine
Vrinzen, Stadhouders, Bloemendal et al. · 2026 · BMJ open
Concentration of care and collaborations between hospitals increasingly reorganise oncological care into Comprehensive Cancer Networks (CCNs), aiming to improve care outcomes and reduce costs. This study aims to evaluate the effect of four…
View details →DOI: 10.1136/bmjopen-2025-100070 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Bilan Yang, Xiaoli Xi, Hongsheng Yu et al. · 2024 · Cancer Reports
Abstract Background The optimal treatment strategy for early‐stage hepatocellular carcinoma (HCC) remains controversial, specifically in regard to surgical resection (SR) and ablation. The aim of this study was to investigate the impact of SR and ablation on recurrence and prognosis in early‐stage HCC patients, to optimize treatment strategies and improve long‐term survival. Methods A retrospective analysis was conducted on 801 patients diagnosed with Barcelona Clinic Liver Cancer (BCLC) stage 0/A HCC and treated with SR or ablation between January 2015 and December 2019. The effectiveness and
View details →DOI: 10.1002/cnr2.2030 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Tomoko Hyakumura, Tomoko Hyakumura, Ulises Aregueta-Robles et al. · 2021 · Frontiers in Neuroscience
Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson’s disease and more recently, in psychiatric conditions like obsessive compulsive disorder. Electrode-tissue interfaces that support safe and effective targeting of specific brain regions are critical to success of these devices. Development of directional electrodes that activate smaller volumes of brain tissue requires electrodes to operate safely with higher charge densities. Coatings such as conductive hydrogels (CHs)
View details →DOI: 10.3389/fnins.2021.761525 Negative / Null Result ReportOpen accessSports medicine
JL Ayers, M DeBeliso, TG Sevene et al. · 2016 · Biology of Sport
Olympic weightlifting movements and their variations are believed to be among the most effective ways to improve power, strength, and speed in athletes. This study investigated the effects of two Olympic weightlifting variations (hang cleans and hang snatches), on power (vertical jump height), strength (1RM back squat), and speed (40-yard sprint) in female collegiate athletes. 23 NCAA Division I female athletes were randomly assigned to either a hang clean group or hang snatch group. Athletes participated in two workout sessions a week for six weeks, performing either hang cleans or hang snatc
View details →DOI: 10.5604/20831862.1201814 Negative / Null Result ReportOpen accessPsychology
sara hasani, abolghasem mehrinezhad, Roshanak khodabakhsh pirkalani · 2020 · مجله علوم روانشناختی
Background: Obsessive-compulsive disorder is one of the most common and disabling psychological disorders. Many studies have investigated the effectiveness of mindfulness and exposure on the improvement of obsessive-compulsive disorder, but the key question is which of the two combinations of exposure, mindfulness, and mindfulness of exposure is most effective on obsessive-compulsive disorder in women? Aims: To compare the effects of exposure, mindfulness and mindfulness-exposure consciousness on combined obsessive-compulsive disorder in Arak women. Method: This was a quasi-experimental study
Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Shingo Hatakeyama, Hayato Yamamoto, Akiko Okamoto et al. · 2012 · International Journal of Nephrology
The oral adsorbent AST-120 has the potential to delay dialysis initiation and improve survival of patients on dialysis. We evaluated the effect of AST-120 on dialysis initiation and its potential to improve survival in patients with chronic kidney disease. The present retrospective pair-matched study included 560 patients, grouped according to whether or not they received AST-120 before dialysis (AST-120 and non-AST-120 groups). The cumulative dialysis initiation free rate and survival rate were compared by the Kaplan-Meier method. Multivariate analysis was used to determine the impact of AST-
View details →DOI: 10.1155/2012/376128 Negative / Null Result ReportOpen accessMedicine
Pius Pum Tseuguem, Télesphore Benoît Nguelefack, Elvine Pami Nguelefack-Mbuyo et al. · 2026 · Scientific Reports
Abstract Extracts of Paullinia pinnata have demonstrated therapeutic effects in monosodium urate (MSU)-induced gout in rats, notably by reducing inflammation and hyperalgesia, as well as enhancing antioxidant activity in vivo. However, their in vitro antioxidant potential and their effects on MSU-stimulated macrophages remain insufficiently explored. This study aims to investigate the in vitro antioxidant properties of P. pinnata, with a particular focus on MSU uptake in stimulated macrophages. The in vitro antioxidant activities of aqueous (AEPP) and methanolic (MEPP) extracts of P. pinnata l
View details →DOI: 10.1038/s41598-026-48124-y 