Negative / Null Result ReportMedicine
Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology
Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…
View details →DOI: 10.1111/ajco.70118 Negative / Null Result ReportMedicine
Whiteside SPH, Gloe LM, Biggs BK · 2026 · Journal of clinical psychology
Objectives Cognitive behavioral therapy (CBT) is the most researched treatment for childhood anxiety disorders (CADs). Improving outcomes and efficiency of CBT will require identifying and optimizing the most efficacious therapeutic…
View details →DOI: 10.1002/jclp.70140 Negative / Null Result ReportMedicine
Virkkunen V, Kero K, Stenholm S et al. · 2026 · Menopause (New York, N.Y.)
Objectives For many women, retirement represents a significant transition in late adulthood, which may result in many alterations in lifestyle habits and behavioral patterns. Several factors known to improve during the retirement…
View details →DOI: 10.1097/gme.0000000000002778 Negative / Null Result ReportMedicine
Shirane K, Kitagawa N, Morishima R et al. · 2026 · Journal of pediatric surgery
Background Pulmonary metastasectomy can improve the survival of children with pulmonary metastases from solid tumors. However, preoperative imaging often suggests chest wall and/or mediastinal invasion, raising concerns about…
View details →DOI: 10.1016/j.jpedsurg.2026.163183 Negative / Null Result ReportMedicine
Lovern A, Watson M, Hollis A et al. · 2026 · AANA journal
Resident registered nurse anesthetists (RRNAs) face high levels of depression, anxiety, and stress (DAS) due to the academic, clinical, and financial demands of graduate anesthesia education. Nature-based mindfulness, which integrates…
View details →DOI: 10.70278/aanaj/.0000001058 Negative / Null Result ReportMedicine
Aydın Güçlü Ö, Demirdöğen E, Hunutlu FÇ et al. · 2026 · BMC infectious diseases
Background Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality among immunocompromised patients, particularly those with hematologic malignancies. The present study aims to evaluate the clinical features,…
View details →DOI: 10.1186/s12879-026-13708-6 Negative / Null Result ReportMedicine
Premkumar A, Arellano E, Heo KY et al. · 2026 · The Journal of arthroplasty
Background The use of short-term postoperative corticosteroid regimens has been reported to improve pain control and decrease opioid consumption following total knee arthroplasty (TKA). The purpose of this study was to evaluate the effect…
View details →DOI: 10.1016/j.arth.2026.04.076 Negative / Null Result ReportMedicine
Nicklas A, Bienger K, Rudari M et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Background Split-thickness skin grafting (STSG) remains the standard for deep second-degree burns, but grafted skin often shows suboptimal biomechanical properties. The dermal substitute MatriDerm® may improve elasticity, structural…
View details →DOI: 10.1016/j.burns.2026.107977 Negative / Null Result ReportMedicine
Lychagin AV, Gritsyuk AA, Elizarov MP et al. · 2026 · Journal of clinical medicine
Background: Robot-assisted total knee arthroplasty (raTKA) improves the precision of component positioning and coronal alignment restoration, but it remains uncertain whether that technical accuracy modifies the clinical effect of…
View details →DOI: 10.3390/jcm15124515 Negative / Null Result ReportMedicine
Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
View details →DOI: 10.1158/2159-8290.cd-26-0403 Negative / Null Result ReportMedicine
Espeche W, Minetto J, Cerri G et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Hypertensive disorders of pregnancy are a leading cause of maternal-fetal morbidity and mortality, with preeclampsia representing a major contributor to adverse outcomes. Ambulatory blood pressure monitoring (ABPM) has improved risk…
View details →DOI: 10.1038/s41440-026-02687-5 Negative / Null Result ReportMedicine
Vollam S, Roman C, Santos M et al. · 2026 · JMIR medical informatics
Background Many studies have evaluated the use of wearable monitoring systems to improve patient safety in hospital. Although some have demonstrated effects on intensive care admissions, there remains little evidence of impact on patient…
View details →DOI: 10.2196/81304 Negative / Null Result ReportMedicine
Mohy N, Sanaie S, Rahnemayan S et al. · 2026 · Beneficial microbes
Oxidative stress is a significant contributor to neuronal damage in multiple sclerosis (MS), marked by an imbalance in reactive oxygen species and antioxidant defences. Probiotics may modulate oxidative stress and improve antioxidant…
View details →DOI: 10.1163/18762891-bja00115 Negative / Null Result ReportMedicine
Gray SL, Liberman M, Onukwufor E et al. · 2026 · American journal of pharmaceutical education
Objectives Ageism remains a pervasive barrier to delivering high-quality health care to older adults. The objective of this scoping review is to describe studies on educational interventions aimed at improving the empathy and attitudes of…
View details →DOI: 10.1016/j.ajpe.2026.101960 Negative / Null Result ReportMedicine
Ishiguro S, Guitard D, Saint-Aubin J · 2025 · Quarterly journal of experimental psychology (2006)
Semantic relatedness of items improves working memory performance. We targeted one type of semantic relatedness, semantic association. The beneficial effect of association is often explained by the spreading-activation process:…
View details →DOI: 10.1177/17470218251392562 Failed Experiment ReportMedicine
Looman MI, Klau MM, Schoenmakers TM et al. · 2026 · Journal of sleep research
While time in bed restriction is a core treatment mechanism of Sleep Restriction Therapy (SRT), empirical research has not yielded a relationship between insomnia improvement and adherence to the prescribed time in bed. We coin this…
View details →DOI: 10.1111/jsr.70339 Negative / Null Result ReportMedicine
Daniel F, El Kouzi Z, Mrad J et al. · 2025 · Updates in surgery
Preoperative use of biologics has been inconsistently reported to be associated with increased frequency of infectious and surgical anastomotic complications in inflammatory bowel disease patients. We aimed to evaluate the rates of 30-day…
View details →DOI: 10.1007/s13304-025-02238-6 Negative / Null Result ReportMedicine
Berger M, Bruggisser F, Schwarz A et al. · 2025 · Physiology & behavior
Objectives To investigate whether a single session of aerobic exercise improves inhibitory control in preadolescent children and whether this effect is mediated by changes in parasympathetic activity. Design In this experimental study, an…
View details →DOI: 10.1016/j.physbeh.2025.114820 Negative / Null Result ReportMedicine
Stark BC, Alexander JM, Stockrahm E et al. · 2026 · American journal of speech-language pathology
Purpose This study examined the role of inner speech-defined here as the subjective experience of covert lexical access-in naming recovery following semantic feature analysis (SFA) treatment in individuals with aphasia. Specifically, it…
View details →DOI: 10.1044/2026_ajslp-25-00363 Negative / Null Result ReportMedicine
Bandura A, Mierzejewska M, Cytawa W et al. · 2026 · Cancers
Background: Oligometastatic non-small cell lung cancer (OMD NSCLC) represents a distinct clinical state with limited metastatic spread, where local ablative therapies (LAT) combined with systemic treatment may improve outcomes. Accurate…
View details →DOI: 10.3390/cancers18121880 Negative / Null Result ReportMedicine
Burton M, Haft S, Fiskeaux M et al. · 2026 · Journal of anxiety disorders
Background Prolonged Exposure (PE) is an effective treatment for PTSD and clarification of mechanisms of change can inform training and continued improvements. Posttraumatic cognitions have been shown to predict subsequent symptom change…
View details →DOI: 10.1016/j.janxdis.2026.103186 Negative / Null Result Report
Sato T · 2025 · Preprint
Objectives: The Eight-chop technique is a mechanically based nuclear segmentation method designed to improve surgical efficiency and reduce intraocular tissue stress during phacoemulsi-fication. Early postoperative aqueous flare serves as…
View details →DOI: 10.20944/preprints202512.0021.v1 Negative / Null Result Report
KARAASLAN F, BİNBAŞIOĞLU DD, ÇEKİÇ EC et al. · 2026 · Preprint
Abstract Objective To assess long-term outcomes of immediate implant placement in endodontic, periodontal and endo–perio compromised sockets and in sites immediately replaced after failed implant explantation, and to examine the roles of…
View details →DOI: 10.21203/rs.3.rs-9259324/v1 Negative / Null Result ReportMedicine
Noroozi Gilandehi S, Shoubash L, Leyendecker J et al. · 2026 · Journal of neurosurgery. Spine
Objective Although patients often report improvements in pain and functional capacity after endoscopic lumbar spine surgery, objectively measured real-life physical activity may differ from that reported. This multicenter prospective study…
View details →DOI: 10.3171/2026.1.spine25926 Negative / Null Result ReportOpen accessMedicine
Zournatzidis P, Vorria P, Krana E et al. · 2026 · Personality and mental health
Mentalizing is a socio-cognitive capacity that develops within early attachment relationships, but institutional care may disrupt this process. Although adoption significantly improves developmental outcomes, it remains unclear whether…
View details →DOI: 10.1002/pmh.70084 Negative / Null Result ReportMedicine
Ballinger TJ, Zhao F, Jiang G et al. · 2026 · Cancer
Background Black patients with breast cancer experience higher rates of taxane-induced peripheral neuropathy (TIPN), which may compromise chemotherapy dose delivery and health-related quality of life (HRQOL). Using the prospective…
View details →DOI: 10.1002/cncr.70466 Negative / Null Result ReportMedicine
Fosstveit SH, Feron J, Lohne-Seiler H et al. · 2026 · BMC sports science, medicine & rehabilitation
Background High-intensity interval training (HIIT) was originally designed to improve athletic performance, but a growing body of research over the past decade has highlighted its positive impact on various other health outcomes. However,…
View details →DOI: 10.1186/s13102-026-01750-5 Negative / Null Result ReportMedicine
Freeman D, Rosebrock L, Waite F · 2026 · Schizophrenia research
Background Initial patient perceptions of a treatment's credibility, and expectations for improvement, have been shown to predict to a small degree outcomes for common mental health disorders. This study aimed to discover: how patients…
View details →DOI: 10.1016/j.schres.2026.03.005 Negative / Null Result ReportMedicine
Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…
View details →DOI: 10.1177/10781552251415528 Negative / Null Result ReportMedicine
Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis
Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…
View details →DOI: 10.1080/15504263.2025.2606022 