A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
1896 results for "Mpro" · page 31 of 64
Marie A, Leclere JC, Fleming Y et al. · 2026 · Audiology & neuro-otology
Introduction Cochlear implantation is the standard of care for children with severe-to-profound sensorineural hearing loss, offering substantial improvements in speech intelligibility, tonal audiometry perception, language acquisition, and…
He CZ, Qiu Q, Lai H et al. · 2026 · BMC ophthalmology
This study aimed to evaluate whether a combination of optical coherence tomography (OCT) and OCT angiography (OCTA) parameters could improve the discrimination between clinically diagnosed normal-tension glaucoma (NTG) and non-glaucomatous…
Tawhari I, Park S, Yamani F et al. · 2026 · Frontiers in nephrology
Objective Calcineurin inhibitors, such as tacrolimus, are associated with long-term nephrotoxicity and renal allograft dysfunction despite evidence of improved kidney transplantation outcomes. Consequently, minimizing calcineurin inhibitor…
Schemel-Suarez M, Egido-Moreno S, Martínez-Lizan I et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Background Dental anxiety frequently compromises patient cooperation and outcomes during third molar (3M) extraction prompting the use of nonpharmacological strategies such as detailed written information. Evidence on reducing preoperative…
Chen R, Li D, Jia B et al. · 2026 · PeerJ
Background This study examined whether ischemic preconditioning (IPC) improves lower-limb anaerobic performance and neuromuscular function in female athletes. Methods Twenty-two female second-level athletes were randomly assigned to an IPC…
Armah L, Tan L, Branning R et al. · 2026 · Epilepsy & behavior : E&B
Aims To evaluate whether improvements in depressive symptoms, epilepsy self-efficacy, and perceived stigma mediate the association between the SMART intervention and epilepsy self-management. Methods 160 people with epilepsy were enrolled…
Dobashi S, Hotoge S, Kikuchi A et al. · 2026 · Scientific reports
Excessive alcohol consumption contributes to mortality and productivity losses, yet evidence for workplace-based substitution interventions remains limited. This randomized controlled trial examined whether providing non-alcoholic…
Gouda A, Arshad MZ, Andrysek J · 2026 · PloS one
Gait training is an important part of rehabilitation for prosthetic users, improving mobility and long-term health outcomes. This study investigated the effects of rhythmic auditory stimulation (RAS) on gait symmetry and overall movement…
Kong K, Qiang Z, Yang Y et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS
Background Surgical robots offer improved precision and stability for laparoscopy; nevertheless, their limited portability and high cost impede broader clinical applications. Methods This paper proposes a hand-held surgical robot with an…
Umutoni V, Eavou R, Almirol E et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)
Background Black and Hispanic/Latino sexual gender minorities are disproportionately affected by HIV. Structural determinants of health, such as health insurance coverage, drive care engagement and improve HIV care outcomes. Methods Black…
Zheng S, Shi Y, Feng Z et al. · 2026 · Journal of wound care
Objective The efficacy of acellular dermal matrix (ADM) in immunocompromised patients' wounds has been little studied. The present study aimed to determine the wound healing effects of ADM in immunocompromised patients compared with…
Portell AL, Niec LN · 2026 · Behavior modification
Time-out from positive reinforcement (TOPR) is an effective limit-setting strategy for decreasing disruptive behaviors in young children. However, most publicly available information on TOPR (e.g., social media and other internet outlets)…
Vujović T, Begić Biškup K, Bojanić K et al. · 2026 · Scientific reports
Organic solvents are routinely used to dissolve poorly water-soluble chemicals in zebrafish-based assays. However, their intrinsic biological activity may confound behavioural endpoints and compromise data interpretation. This study…
Heinonen K, Kaprio J, Trias T et al. · 2026 · Twin research and human genetics : the official journal of the International Society for Twin Studies
The purpose of this cross-sectional study was to investigate knowledge about multiple-birth families among midwives and public health nurses working in maternity and child health clinics in Finland. The data were collected with a Finnish…
Wan L, Xie B, Shuda M et al. · 2026 · Molecular therapy : the journal of the American Society of Gene Therapy
CD8+ T cell targeting of the conserved SARS CoV2 RNA-dependent RNA polymerase (RdRp, nsp12) may offer a means for cross-protection against diverse coronavirus strains. Native RdRp, however, displays primary sequence immunoevasion (PSI)…
Vidon M, Wang X, Costes L et al. · 2026 · Clinics and research in hepatology and gastroenterology
Background and study aims Educational interventions have been proposed to improve adherence to bowel preparation instructions. We evaluated whether adding a short instructional video to standard written and oral information improves bowel…
M MM, M G, R R et al. · 2026 · Preprint
Background: Vitamin D optimizes musculoskeletal function and athletic performance, yet optimal supplementation protocols remain unclear. Methods: In this double-blind RCT, 18 professional female soccer players were randomized during autum…
Choo LY, Zheng W, Wen S et al. · 2026 · Journal of the American Pharmacists Association : JAPhA
Background Patients with opioid use disorder encounter challenges obtaining buprenorphine (BUP) at pharmacies, increasing their risk of treatment non-adherence and illicit drug use. Objectives The purpose of this quality improvement (QI)…
Traylor AM, Bell EA, Lewis NCM et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective We investigated the impact of leaders' interprofessional teamwork behaviors on NICU staff perceptions of teamwork processes, trust, psychological safety, and voice behavior. Study design To develop a measure of leaders'…
Fältström A, Hedevik H, Ardern CL et al. · 2026 · The Journal of orthopaedic and sports physical therapy
OBJECTIVE: To evaluate the efficacy of internet-delivered psychological support-the BAck iN the Game (BANG) intervention-after anterior cruciate ligament reconstruction (ACLR) for improving return to sport (RTS). DESIGN: Randomized…
Ichishima J, Nakakariya M, Kimura H · 2026 · Scientific reports
Narcolepsy type 1 (NT1) is caused by a significant loss of orexin-producing neurons. In clinical trials, multiple orexin receptor 2 (OX2R)-selective agonists (e.g., danavorexton, TAK-994, and oveporexton) improved wakefulness and decreased…
Yang Y, Zhou J, Zhao L et al. · 2026 · BMC pregnancy and childbirth
Introduction Compared with early cord clamping (ECC), delayed cord clamping (DCC) facilitates improved placental transfusion and increases blood volume in singleton pregnancies. However, evidence supporting the use of DCC in twins…
Werner C, Ullrich P, Degli Angeli L et al. · 2026 · Age and ageing
Persistent mobility limitations after inpatient rehabilitation are common in older adults with cognitive impairment (CI). Home-based exercise interventions can improve locomotor capacity during this vulnerable period; however, evidence…
Muñoz-Tebar N, Lucas-González R, Muñoz-Bas C et al. · 2026 · Food chemistry
This study investigates the use of quinoa oil emulsion as a novel plant-based ingredient to improve the nutritional quality of fresh goat cheese. Quinoa oil emulsions (3 and 6 g/L) were characterized and incorporated in fresh cheese. The…
Cheever K, Kalvesmaki A, Swan AA et al. · 2026 · Brain injury
Background This study aimed to explore what treatments were sought by post-9/11 Veterans with and without a formal diagnosis related to their long-term dizziness following completion of a Comprehensive Traumatic Brain Injury Evaluation…
Rovere G, Cuyabano BCD, Phocas F · 2026 · Preprint
ABSTRACT Breeding programs are essential in aquaculture, improving economically and environmentally important traits. In aquaculture systems, animals are raised in large groups, where social interactions are frequent and can influence…
Shehu E, Pieper D, Albrecht HC et al. · 2026 · JBI evidence implementation
Introduction Pre-operative stoma site marking is a strongly recommended practice for preventing complications and improving the health-related quality of life of intestinal stoma patients. Despite its benefits, this practice is not…
Suksathien Y, Suarjui J, Tippimanchai T et al. · 2026 · International orthopaedics
Purpose Intraoperative calcar fracture (IOCF) can compromise initial stability, leading to stem subsidence and instability. We aimed to compare 2-year complications and revision rates between patients who sustained IOCF and matched…
Jenkins TL, Darden K, Pourdeyhimi B et al. · 2026 · Journal of biomechanics
Synthetic polymer scaffolds with aligned fibers permit engineered tendon development and the formation of an aligned, collagen rich matrix. However, many tissue engineered constructs cannot withstand physiologically relevant loads. Both…
Le Baron M, David G, Ward BA et al. · 2026 · Journal of orthopaedic trauma
Objectives To evaluate whether the use of intraoperative 3D fluoroscopy during acetabular fracture fixation reduces the rate of unplanned returns to the operating room and improves radiographic quality of reduction without increasing…